RUI: Cellular and Biochemical Mechanisms of Allelochemical Toxicity of L-azetidine-2-carboxylic Acid to Helicoverpa zea

食草昆虫面临着一个强大而多样的 一系列天然植物毒素 我们已经证明， 玉米穗虫Helicoverpa zea（Boddie）是一种多食性昆虫， 对1-氮杂环丁烷-2- 羧酸（AZC），一种天然存在的高等植物同系物 脯氨酸 以含有AZC的饮食饲养的幼虫 发育迟缓并表现出各种发育障碍 病变 AZC毒性通常在幼虫蜕皮期间表达 在幼虫-蛹蜕皮时尤为明显。 如果 幼虫-蛹蜕皮，蛹经常变形; 通常表现出大的非硬化区域。 细胞和 AZC毒性的生化机制和许多 化感物质大部分是未知的。 对细胞/ 组织形态学和生物化学事件之前和/或 在H.玉米将增加 了解化感物质的保护作用， 植物-食草动物的相互作用，并有可能进一步 发展不需要工业控制的虫害控制 农药

Insect herbivores are confronted with a formidable and diverse array of naturally occurring plant toxins. We have shown that the corn earworm, Helicoverpa zea (Boddie), a polyphagous insect, is highly sensitive to the antimetabolic effects of 1-azetidene-2- carboxylic acid (AZC), a naturally occurring higher plant homolog of proline. Larvae reared on a diet containing AZC suffer developmental retardation and exhibit various developmental lesions. AZC toxicity is typically expressed during larval molts and it is particularly evident at the larval-pupal molt. If larval-pupal ecdysis occurs, the pupae are frequently deformed; often exhibiting large, nonsclerotized areas. The cellular and biochemical mechanisms for the toxicity of AZC and many allelochemicals are largely unknown. This study of the cell / tissue morphological and biochemical events that precede and / or accompany the symptoms of AZC toxins in H. zea will increase understanding of the protective role of allelochemicals in plant-herbivore interactions, and has the potential to further development of insect pest controls which do not require industrial pesticides.