Sterically Hindered Ligands and Studies of Their Biomimetic Metal Complexes

这项研究将集中于合成受阻的双齿配体，旨在加强金属(铜)周围不寻常的配位数和/或几何构型。这项工作旨在为理解天青等金属蛋白的化学和光谱性质提供更好的模型。%有了这个RUI奖，合成有机计划支持圣地亚哥大学化学系的Patricia S.Traylor博士的研究。研究的重点将是使用受阻配体来帮助理解重要类别的金属酶的非凡光谱和性质，并让本科生参与有意义的研究经历。

This research will focus on the synthesis of hindered bidentate ligands designed to enforce unusual coordination numbers and/or geometries around a metal (copper). The work seeks to provide better models for understanding the chemical and spectroscopic properties of metalloproteins such as azurin. %%% With this RUI award, the Synthetic Organic Program is supporting the research of Dr. Patricia S. Traylor of the Department of Chemistry at the University of San Diego. The focus of the research will be to use hindered ligands to help understand the extraordinary spectra and properties of important classes of metalloenzymes and to involve undergraduates in a meaningful research experience.