Multiuser Fast NMR Field Cyc#lng Instrument

该项目提出建设一个强大的， 变场核磁共振谱仪 （范围从0到2特斯拉），用于研究 松弛和分子动力学在一个广泛的范围内， 材料，包括液晶、磷脂 膜和聚合物，以及 生物无机化合物场循环核磁共振（FC-NMR）是一种 创新和相当新技术，如FC-NMR 光谱仪不是商业上可获得的。主要 FC-NMR光谱仪的应用将获得 关于IH，2 H， 固体和液晶中的~（19）F和~（31）P核 各种材料在低至 中间 磁场强度（0至2特斯拉），其中测量 使用标准NMR方法是困难的或不可能的。的 弛豫机制将产生新的信息， 各种材料中分子的动力学 研究了对低磁场弛豫的认识 场（低频）区域是必不可少的，以获得任何 全面了解分子特性， 固体、液晶和膜。FC-NMR 还将使用光谱仪获取信息 关于四极核周围的电荷分布， 如生物无机物中的~ 2 H、~（14）N、~（17）O、~（59）Co等， 这对于详细了解 它们的反应化学和它们在酶中的作用 机制等

This project proposes the construction of a powerful, variable-field nuclear magnetic resonance (NMR) spectrometer (range from 0 to 2 Tesla) for the investigation of relaxation and molecular dynamics in a broad range of materials, including liquid crystals, phospholipid membranes, and polymers, as well as bonding structure in bioinorganic compounds. Field-cycling NMR (FC-NMR) is an innovative and rather new technique and such FC-NMR spectrometers are not commercially available. The major application of the FC-NMR spectrometer will be to obtain novel information on the relaxation properties of IH, 2H, l9F, and 31P nuclei in the solid and liquid-crystalline states of various materials at low to intermediate magnetic fields strengths (0 to 2 Tesla), where measurements using standard NMR methods are difficult or impossible. The relaxation mechanisms will yield new information regarding the dynamics of the molecules in the various materials to be studied. Knowledge of the relaxation in the low magnetic field (low frequency) region is essential to obtain any comprehensive understanding of the molecular properties in solids, liquid crystals, and membranes. The FC-NMR spectrometer will also be used to obtain information regarding the charge distribution around quadrupolar nuclei, such as 2H, 14N, 17O, and 59Co in bioinorganic substances, which is essential to achieve a detailed understanding of their reaction chemistry and their role in enzyme mechanisms.