Regulation of Complex Behavior by Neuropeptides

虽然昆虫的神经系统相对简单， 并没有阻止这些动物进行复杂的 行为。 一种昆虫的行为导致了人类 痛苦是一种让蚊子找到宿主的痛苦。 血的大餐 使用我们所知道的各种化学和视觉信号 蚊子能够定位我们并摄取我们的 血液，并在此过程中传播往往致命的疾病。 Klowden博士是国际知名的蚊子专家 在复杂环境中的行为。 他已经确定了 当昆虫本身控制自己的行为并且不寻求 主持人 利用这些不作为的时期，克洛登博士确定了一个 一种新的FMRFamide相关神经肽，伊蚊头肽1， 特异性抑制黄热病的宿主寻找行为 蚊子，并防止他们吸血。 使用 非常困难的技术/手术技术，他可以开始 为了解开伊蚊头肽1阻止 蚊子寻找宿主的行为发生，以及如何 激素与其他因素相互作用。 结果从这些 基础研究可能会带来新的发现， 将极大地影响神经内分泌学的进展， 昆虫与昆虫行为 此外，基本调查结果得出 从这项研究应该提供必要的信息需要 制定更好的战略， 蚊子的数量和它们通过蚊子传播的疾病 它们的吸血活动

Although the insect nervous system is relatively simple, it has not prevented these animals from engaging in quite complex behaviors. One such insect behavior that has led to much human suffering is the one that allows a mosquito to find a host for a meal of blood. Using various chemical and visual signals that we humans give off, mosquitos are able to locate us and ingest our blood, and in the process transmit often deadly disease agents. Dr. Klowden is an internationally renown expert on mosquito behavior in the complex environment. He has identified times when the insect itself controls its behavior and does not seek a host. Using these periods of inaction, Dr. Klowden identified a novel FMRFamide-related neuropeptide, Aedes Head Peptide 1, that specifically inhibits host seeking behavior in the yellow fever mosquito, and prevents them from feeding on blood. Using extremely difficult technical/surgical techniques, he can begin to unravel the mechanisms by which Aedes Head Peptide 1 prevents mosquito host-seeking behavior from occurring, and how this hormone interacts with other factors. The results from these fundamental studies are likely to lead to new discoveries that will substantially impact progress in the neuroendocrinology of insects and insect behavior. In addition, basic findings derived from this research should provide essential information needed for the development of better strategies for the control of populations of mosquitoes and the diseases that they transmit via their blood-feeding activities.