Cardiac Fluid Dynamics and the Immersed Boundary Method

9302545 Peskin该奖项将支持心脏的计算研究、浸没边界方法的开发，以及生物界涉及浸入边界方法的软件的生产。该项目的第一个组成部分将是创建一个足够有效和现实的心脏计算机模型，作为计算心脏功能的实用科学工具。该项目的一个目标是产生用于生物实验的成像模式(例如彩色多普勒血流，MRI)的模拟，以便计算机实验的输出可以直接与实验数据进行比较。这种类型的输出使模拟数据和实际数据之间的直接比较成为可能。在两者一致的程度上，这支持了该模型的有效性。这种比较的另一个好处是：如果模型有效，则可以使用模拟数据来增强可视化技术。该项目的软件部分将与匹兹堡超级计算中心共同开发。该项目得到了计算数学、生理学和计算生物学项目的支持。***

9302545 Peskin This award will support computational studies of the heart, the development of the immersed boundary method, and the production of software involving the immersed boundary method for the biological community. The first component of the project will be the creation of a computer model of the heart that is efficient enough and realistic enough to be a practical scientific tool for the computational investigation of cardiac function. One goal of the project is to produce simulations of imaging modalities (e.g. color-Doppler flow, MRI) that are used in biological experimentation so that the output from the computer experiment can be directly compared to experimental data. This type of output make possible a direct comparison between simulated and actual data. To the extent that the two agree, this lends support to the validity of the model. Another benefit from such comparison is this: if the model is valid \, then the simulated data can be used to enhance the visualization technique. The software component of this project will be develop in conjunction with the Pittsburgh Supercomputing Center. The project is being supported by the Computational Mathematics, the Physiology, and the Computational Biology programs. ***