Next Generation Photocatalysis for Chemical Synthesis and Manufacture

该项目旨在发现活化有机分子中需要能量的键的新方法，作为化学合成的一般策略。该项目的一个关键概念进展是多光子光氧化还原催化的发展，作为一种强有力的工具来激活传统上不反应的，但丰富的有机分子中的化学键，包括烷烃和烯烃原料中的C-H键。随着从精细化学品生产到药物发现等领域的应用，这项研究的总体目标是建立新的键活化反应，并展示对新药物，农用化学品和先进化学品制造工艺的发明的转化，这些工艺将产生社会影响。

This project aims to discover new methods for the activation of energy demanding bonds in organic molecules as a general strategy in chemical synthesis. A key conceptual advance in this project is the development of multiphoton photoredox catalysis as a powerful tool to activate traditionally unreactive, yet abundant chemical bonds in organic molecules including C-H bonds in alkane and olefin feedstocks. With application in fields that range from fine chemical production to drug discovery, the overarching aim of this research is to establish new bond activation reactions and to demonstrate translations to the invention of new pharmaceuticals, agrochemicals and advanced chemical manufacturing processes that will have societal impact.