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Small molecule control of the functional dynamics in cardiac potassium channels.

Small molecule control of the functional dynamics in cardiac potassium channels.
心脏钾通道功能动力学的小分子控制。
批准号:
224761
负责人:
Noskov Sergei
金额:
$40.66万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-03-01 至 2016-03-01

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中文摘要
翻译
被称为钾通道的膜蛋白的功能障碍与广谱心律失常有关。控制心律失常的确切机制以及它如何由相关蛋白质决定还有待了解。的焦点
英文摘要
Malfunctioning of membrane proteins, known as potassium channels, is associated with a broad spectrum of cardiac arrhythmias. The exact mechanism that governs arrhythmias and how it is determined by proteins involved is yet to be understood. The focus of
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会议论文
Lipid-dependent modulation of cardiac ion channel activity as an anti-arrhythmic therapy in long-QT syndrome
  • 批准号:
    369499
  • 项目类别:
    Operating Grants
  • 资助金额:
    $48.76万
  • 财政年份:
    2017
  • 负责人:
    Noskov Sergei
  • 依托单位:
Mechanism of the high-affinity ligand binding and selective ion permeation in voltage-gated K-channels
  • 批准号:
    172724
  • 项目类别:
    Salary Programs
  • 资助金额:
    $21.86万
  • 财政年份:
    2008
  • 负责人:
    Noskov Sergei
  • 依托单位:
海外基金