Symposium: "Origins and Evolution of Animal Body Plans"

这项提案要求提供部分资金，以支助定于1994年10月27日至30日在布卢明顿的印第安纳州大学校园内举行的一次专题讨论会。 研讨会的题目是“动物身体计划的起源和演变”。 动物体型的起源和它们在进化中的变化问题已经成为一个相当令人兴奋的话题。 来自古生物学的关于寒武纪辐射的模式和历史的证据提供了一个新的数据和见解来源。 分子遗传学现在也开始对理解这些事件产生重要影响。 最后，最近在发育遗传学方面的爆炸性进展揭示了进化的重要机制和在多种动物的发育中起主要调节作用的基因。 古生物学家、发育生物学家、分子生物学家和进化生物学家之间的联系已经变得引人注目，并且已经开始解决动物身体计划何时以及如何出现的主要问题，以及它们在进化过程中如何被修改。 这次会议是在印第安纳州大学印第安纳州分子和细胞生物学研究所主持下举行的年度系列会议中的第八次。 以前的主题包括“发育的遗传和分子分析”，“蛋白质作为机器”和“蛋白质修饰的生物调节”。 组织委员会的目标是召集一个由对中心主题的主要方面作出贡献的学科领导人组成的国际小组，介绍其学科贡献的当前想法。 以往的经验表明，综合性会议可以产生新的科学综合。 就这一主题进行这种互动的时机是适当的。 虽然现有的会议讨论了这些问题的某些方面，但没有一次会议试图将所有的办法充分结合起来。 没有一个学会专门致力于发展的演变，通过现有的学会会议也无法取得同等的成果。

This proposal requests funds in partial support of a symposium to be held on the campus of Indiana University, Bloomington, from October 27 - 30, 1994. The symposium is entitled, "Origins and evolution of animal body plans". The problem of the origin of animal body plans and their modification in evolution has become a topic of considerable excitement. Evidence from paleontology on the pattern and history of the Cambrian radiation provides one new source of data and insight. Molecular phylogeny is now beginning to make an important impact on understanding these events as well. Finally, the explosive recent progress in developmental genetics has revealed both important mechanisms subject to evolution and genes that play major regulatory roles in development of a wide diversity of animals. The interface between paleontologists, developmental biologists, molecular biologists, and evolutionary biologists has become striking, and has begun to resolve major problems in when and how animal body plans appeared and how they have been modified in evolutionary time. The meeting is the eighth in an annual series presented under the auspices of the Indiana Institute for Molecular and Cellular Biology at Indiana University. Previous topics have included "The genetic and molecular analysis of development", "Proteins as machines", and "Biological regulation by protein modification". The objectives of the organizing committee are to bring together an international group of the leaders in the disciplines that are contributing to major aspects of the central theme to present the current ideas contributed by their disciplines. Previous experience has shown that integrative conferences can produce new syntheses in science. The timing is appropriate to achieve this kind of interaction on this topic. Although existing meetings deal with some aspects of these subjects, no one meeting has attempted to fully integrate all of the approaches. There is no society devoted to the evolution of development, and equivalent results cannot be met through existing society meetings.