Metazoan Phylogeny by rRNA Sequencing

通过 rRNA 测序进行后生动物系统发育

• 批准号: 8818044
• 负责人: Rudolf Raff
• 金额: $ 21.66万
• 依托单位: Indiana University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-01-15 至 1992-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8818044&HistoricalAwards=false
• 关键词: Metazoan; Phylogeny; rRNA; Sequencing

The evolutionary relationships among the major animal groups has been debated for centuries, but the advent of molecular sequencing techniques now affords a new and data-rich view of the problem. Dr. Rudolph Raff, a developmental biologist, has assembled a team of molecular biologists who will establish the RNA sequences for particular segments of the ribosomal genome in a variety of invertebrate phyla. They will concentrate their efforts on the pseudocoelomate and acoelomate worm phyla, the arthropods, and the cnidarians (corals, anemones). New techniques will be used for sampling genetic material from microbial organisms, and the sequence data will be analyzed using a variety of approaches. The proposed research will have wide impact on invertebrate zoologists and evolutionary biologists. The data resource to be amassed will be strutinized and re-analyzed by countless other researchers.

主要动物群体之间的进化关系已经争论了几个世纪，但分子测序技术的出现现在为这个问题提供了一个新的、数据丰富的观点。 发育生物学家 Rudolph Raff 博士组建了一个分子生物学家团队，他们将建立各种无脊椎动物门中核糖体基因组特定片段的 RNA 序列。 他们将集中精力研究拟腔皮动物和无腔皮蠕虫门、节肢动物和刺胞动物（珊瑚、海葵）。 新技术将用于从微生物中采集遗传物质，并使用多种方法分析序列数据。 拟议的研究将对无脊椎动物学家和进化生物学家产生广泛影响。 将收集的数据资源将由无数其他研究人员进行验证和重新分析。