RUI: Rates and Mechanism of Grignard Reagent Formation by In situ Photomicrography of Magnesium Surfaces and Scanning Electrochemical Microscopy

Walter Bowyer和他在霍巴特学院和威廉史密斯学院的本科生将在分析和表面化学项目为期42个月的持续资助下研究格氏试剂形成的机制。反应的金属镁的表面将被表征使用显微摄影，扫描电化学显微镜，和动力学研究。本研究的目的是对烷基卤化物与金属镁反应形成合成重要的格氏试剂时所涉及的表面过程有一个基本的、详细的了解。格氏试剂是最常用的有机试剂之一，然而，控制这些物种生产的因素尚不清楚。在这个为本科生设计的研究项目中，Bowyer教授和他的学生将表征金属镁表面发生的试剂形成机制。这些研究的结果将允许更好地控制这些在商业过程中广泛使用的非常有用的试剂的合成。

Walter Bowyer and his undergraduate students at Hobart and William Smith Colleges will investigate the mechanism of Grignard reagent formation with the support of this forty-two month continuing grant from the Analytical and Surface Chemistry Program. The surface of the reacting magnesium metal will be characterized using photomicrography, scanning electrochemical microscopy, and kinetic studies. The goal of this research is to develop a fundamental, detailed understanding of the surface processes involved when alkyl halides react with metallic magnesium to form synthetically important Grignard reagents. Grignard reagents are among the most commonly utilized organic reagents, however, the factors controlling the production of these species are not well understood. In this research project, designed for undergraduate participation, Professor Bowyer and his students will characterize the mechanism of reagent formation occuring at the surface of magnesium metal. The results from these studies will permit much better control of the synthesis of these extraordinarily useful reagents that are employed broadly in commercial processes.