Determination of Water and Cryoprotectant Transport in Engineered Tissues Using Magnetic Resonance Imaging

9410428胡贝尔这项研究计划补助金旨在帮助首席研究人员准备一份建议书，以促进磁共振成像应用的初步研究，以测量合成真皮替代物中水和冷冻防护剂的传输情况。还将对使用局部核磁共振波谱的可行性进行初步评估，以确定渗透和平衡过程中渗透损害的程度。这些研究为后续真皮替代物和其他工程组织中转运问题的实验和理论研究奠定了基础。***

9410428 Hubel This Research Planning Grant was designed to aid in the preparation of a proposal by the principal investigator to facilitate preliminary studies in the application of magnetic resonance imaging to measure the transport of water and cryoprotective agent in a synthetic dermal replacement. A preliminary assessment of the viability of using localized nuclear magnetic resonance spectroscopy will also be examined to determine the extent of osmotic damage during the permeation and equilibration processes. These studies provide the foundation for subsequent experimental and theoretical studies on transport issues in the dermal replacement as well as other engineered tissues. ***