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Molecular mechanisms of natural killer (NK) and innate lymphoid cell (ILC) development and function in health and disease

Molecular mechanisms of natural killer (NK) and innate lymphoid cell (ILC) development and function in health and disease
自然杀伤细胞（NK）和先天淋巴细胞（ILC）在健康和疾病中发育和功能的分子机制
批准号：
323184
负责人：
Carlyle James R
金额：
$49.0万
依托单位：
Sunnybrook Research Institute (Toronto, Ontario)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2015
资助国家：
加拿大
项目状态：
已结题
起止时间：
2015-03-01 至 2020-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=323184&lang=en
关键词：
Cancer Colitis Cytomegalovirus Development Gene Regulation Immune Evasion Infection Innate Immunity Innate Lymphoid Cells (Ilc) Natural Killer (Nk) Cells

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中文摘要
翻译
先天免疫系统保护我们免受致病菌、病毒和癌症的侵害，也有助于维持粘膜屏障（如皮肤、肠道和肺部）的正常组织功能。自然杀伤细胞（NK）是1型先天淋巴细胞c的一个亚群
英文摘要
The innate immune system protects us from pathogenic bacteria, viruses, and cancer, and also helps to maintain normal tissue function at mucosal barriers, such as the skin, gut, and lungs. Natural killer (NK) cells are a subset of type-1 innate lymphoid c
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Molecular evolution of self-nonself discrimination by paired NKR-P1 receptors, self ligands, and viral immunoevasins
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