Acquisition of Core DNA Sequencing Instrumentation

这是对核心DNA测序仪器的请求，以服务于一群活跃的、联邦资助的研究人员和几个培训项目。该仪器将包括一台DNA测序仪和几个辅助设备，包括一台寡核苷酸合成器、热循环仪、一台质粒制备设备、一台荧光仪以及用于DNA序列分析的联网计算机设备和软件。该设施将为几个实验室服务，在这些实验室，DNA测序是积极研究项目的组成部分，还将作为通过自动化RFLP分析进行基因组研究的场所。该设施的另一个用途是靠近生物技术教学实验室，本科生和研究生将有机会在那里接受设备培训。这个教学实验室也是我们为大学教职员工提供的NSF生物技术暑期项目的地点，他们也将从培训机会中受益。罗格斯大学纽瓦克校区是一个独特的研究中心，汇集了一个规模较小但专注于研究的社区，他们坚定地致力于本科生、研究生，特别是少数族裔教育。在过去的10年里，我们为校园增加了超过25名新的研究人员。这些新教师都成功地为他们的研究争取到了联邦资金，并共同努力改善了校园内的教育机会。我们广泛资助的教育项目证明了这一点，这些项目包括：NIH少数民族生物医学研究支持、NIH桥梁到文凭项目奖、NSF计算机教育项目、NSF暑期项目和霍华德·休斯医学院本科科学项目。这一核心DNA测序设施的增加将显著增强我们教师在研究和教育方面竞争未来资金的能力。它将促进我们简单的测序需求，并帮助我们在分子进化领域吸引拟议的新教师。

This is a request for core DNA sequencing instrumentation to serve a group of active, federally-funded research faculty and several training programs. The instrumentation will include a DNA sequencer and several supporting items, including an oligonucleotide synthesizer, thermal cyclers, a plasmid preparation device, a fluorometer, and networked computer equipment and software for DNA sequence analysis. The facility will serve several laboratories where DNA sequencing is an integral part of active research projects, and will also serve as a site for genomic study through automated RFLP analysis. An additional utility of the facility will be its proximity to a biotechnology teaching laboratory, where undergraduate and graduate level classes will have the opportunity to train on the equipment. This teaching laboratory is also the site of our NSF summer program in biotechnology for college faculty, who would likewise benefit from the training opportunity. The Newark campus of Rutgers University is a unique research center combing a small but focused research community with a strong commitment to undergraduate, graduate and particularly minority education. We have added over 25 new research faculty to the campus in the last 10 years. These new faculty have all successfully competed for federal funding of their research and have also worked together to improve the educational opportunities on campus. This is demonstrated by our extensive grant-funded educational programs, including: NIH Minority Biomedical Research Support, NIH Bridges to Baccalaureate Program Award, NSF Computers in Education, NSF Summer Programs, and the Howard Hughes Medical Institute Initiative for Undergraduate Science Program. The addition of this core DNA sequencing facility will significantly enhance our faculty's ability to compete for future funding both in research and education. It will facilitate our simple sequencing needs and help us to attract proposed new faculty in the filed of molecular evolution.