Instrumentation for Instruction in Contemporary Analytical Science

9451709人化学系正在添置仪器，将传统的二年级定量分析课程转变为现代分析科学课程。我们正在开发一门课程，其中基本的潜在主题是暴露在真实的，操作的，现代分析实验室中包含的概念，问题，问题和程序。实现这一目标的关键是提供实验室调查，使低年级学生接触到广泛的现代分析技术。在实验室调查中，实现这一目标的关键是致力于解决有机，生物和环境研究，而不是传统的强调无机样品。调查的类型包括：分离科学；多元素和痕量分析；并结合物理和化学表征。由于其在当代分析实践中的突出地位，分离科学获得了最高的优先权。我们强调HPLC，因为它最符合学生在这个水平的实验室经验，因为它与后续课程的相关性。对于多元素和痕量分析经验，我们选择了两种方法：分析伏安法和原子吸收法。选择分析伏安法是因为它与学生的溶液化学经验相一致；它为多元素痕量分析（溶出伏安法）提供了一个廉价的介绍；它可以应用于金属和有机/生化分析；建立了一种高效液相色谱检测方法。选择原子吸收法是因为它提供了一种更接近标准的商业实验室元素分析技术；它体现了基本的光谱学原理；它比伏安法更适用于元素分析物。结合学生对现代技术的经验，将根据联邦良好实验室规范指南进行实验室操作。

9451709 Perone The Department of Chemistry is acquiring instrumentation to effect transformation of the traditional sophomore quantitative analysis into a course on modern analytical science. We are developing a course where the basic underlying theme is exposure to concepts, problems, issues, and procedures contained in a real, operating, modem analytical laboratory. The key to achieving this is to provide laboratory investigations which expose lower-division students to the broad range of modern analytical technology. Among the laboratory investigations crucial to accomplishing this is the commitment to addressing organic, biological, and environmental studies, instead of the traditional emphasis on inorganic samples. The types of investigations include: separations science; multi-element and trace analysis; and combined physical & chemical characterization. Because of its prominence in contemporary analytical practice, separations science receives the highest priority. We emphasize HPLC because it is most consistent with the students' laboratory experience at this level and because of its relevance to subsequent courses. For the multi-element and trace analysis experience we have selected two approaches: analytical voltammetry and atomic absorption. Analytical voltammetry is selected because it is consistent with the students' experience with solution chemistry; it provides an inexpensive introduction to multi-element trace analysis, (stripping voltammetry); it can be applied to both metallic and to organic/biochemical analytes; and it establishes the technique as a detection approach for HPLC. Atomic absorption is selected because it provides a more nearly standard commercial laboratory technique for elemental analysis; it exemplifies fundamental spectroscopy principles; and it provides broader applicability to elemental analytes than voltammetry. Superimposed on students' experience with modem technology will be laboratory conduc t based on Federal Good Laboratory Practice guidelines.