NSF Young Investigator: Transition Metal Heteroatom Bonds

这个NSF青年研究者奖在无机，生物无机和有机物计划将支持研究过渡金属化合物与杂原子的博士。 耶鲁大学化学系的哈特维希说。 该研究的目标是将有机金属化合物的催化有效性和稳定性带到化学的新领域。 有机化合物含有金属-碳键;在这里，也含有金属-硼键的新物种将被合成和研究其作为催化剂和新材料起始材料的潜力。 钨、铌、铁、钌、铱、镓等化合物的制备，重点是烯烃反应的催化。 此外，将研究碳和氮以及碳和氧的催化金属介导的偶联。 金属-氮系统的研究还将涉及使用有机金属化合物与肽和DNA，其中金属-氮键的光解裂解将有助于鉴定分子内蛋白质折叠过程和其他蛋白质-蛋白质或蛋白质-DNA缔合。

This NSF Young Investigator Award in the Inorganic, Bioinorganic, and Organometallic Program will support research on transition metal compounds with heteroatoms by Dr. John F. Hartwig of the Chemistry Department, Yale University. The goal of the research is to bring the catalytic effectiveness and stability of organometallic compounds to new areas of chemistry. Organometallic compounds contain metal-carbon bonds; here new species which also contain metal-boron bonds will be synthesized and studied for their potential as catalysts and as starting materials for new materials. Tungsten, niobium, iron, ruthenium, iridium and gallium compounds will be prepred and emphasis will be placed on catalysis of reactions of alkenes. In addition, catalytic metal-mediated coupling of carbon and nitrogen and of carbon and oxygen will be studied. Work on metal-nitrogen systems will also involve use of organometallic compounds with peptides and DNA in which photolytic cleavage of the metal-nitrogen bond will aid in the identification of intramolecular protein folding processes and other protein-protein or protein-DNA associations.