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Molecular convergence of insulin and muscle contraction signalling at Rab proteins: Implications for type 2 diabetes

Molecular convergence of insulin and muscle contraction signalling at Rab proteins: Implications for type 2 diabetes
Rab 蛋白上胰岛素和肌肉收缩信号的分子收敛:对 2 型糖尿病的影响
批准号:
228942
负责人:
Klip Amira
金额:
$15.83万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-03-01 至 2014-03-01

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中文摘要
翻译
我们的肌肉是血糖(葡萄糖)的主要调节器。进餐时的葡萄糖储存在肌肉细胞中,供肌肉收缩(运动)时用作燃料。葡萄糖进入的通道是一种叫做GLUT4的蛋白质,这种通道控制着葡萄糖的转运
英文摘要
Our muscles are major regulators of blood sugar (glucose). Meal-time glucose is stored in muscle cells for later use as fuel during muscle contraction (exercise). The gateway for glucose entry is a protein called GLUT4, and this gateway governs glucose st
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Cell biology and physiology of muscle insulin delivery, insulin action and insulin resistance leading to diabetes
Macrophage lipotoxic inflammation: Its mechanism, impact on insulin delivery and interplay with muscle
CANADA RESEARCH CHAIRHOLDER - TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA
  • 批准号:
    241527
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2010
  • 负责人:
    Klip Amira
  • 依托单位:
Regulation of muscle glucose transporters by Rac and Rabs during insulin action and lipotoxicity
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