Modern Applications of Separation Science in the Undergraduate Curriculum
Modern Applications of Separation Science in the Undergraduate Curriculum
批准号:
9551840
负责人:
Michael Burke
金额:
$4.13万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
1995
资助国家:
美国
项目状态:
已结题
起止时间:
1995-05-01 至 1997-04-30
中文摘要
本项目正在开发一个将分离科学的现代应用纳入本科课程的方案。这包括购买新的毛细管电泳(CE)仪器和新的液相色谱(HPLC)功能,以继续升级教学计划中的分析仪器。根据以下思路,正在为初中和高中学生开发新的实验:(a)对高分子量的具有生物学意义的分子进行CE分离和定量(该仪器还为学生提供了首次接触以纳克样品量进行分析的机会);(b)通过液相色谱分离和定量药物化合物(光电二极管阵列检测允许学生进行峰纯度分析);(c)优化液相色谱中溶剂组成和流速,以确定本地生产的富勒烯样品的C60/C70比。该计划允许继续开发新的实验,旨在针对我们学生人口中增长最快的部分-生命科学方向的学生。
英文摘要
This project is developing a program to incorporate modern applications of separation science in the undergraduate curriculum. This includes the acquisition of new capillary electrophoresis (CE) instrumentation and new liquid chromatography (HPLC) capabilities, to continue the upgrade of analytical instrumentation in the teaching program. New experiments are being developed, along the following lines, for students at the junior and senior levels: (a) CE separation and quantitation of biologically significant molecules of high molecular weight (the instrumentation also provides students with their first exposure to analysis with nanogram sample quantities); (b) separation and quantitation of pharmaceutical compounds by liquid chromatography (photodiode array detection allows students to carry out peak purity analysis); and (c) optimization of solvent composition and flow rate in LC to determine the C60/C70 ratio in locally produced fullerene samples. This program allows for the continued development of new experiments, designed to target the fastest growing segment of our student population the life sciences oriented students.
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