U.S.-Korea Cooperative Research on Computational Fluid Dynamics for the Design and Optimization of Cardiac Assist Devices

小行星9602180 该奖项提供资金，允许博士罗杰D。Kamm，机械工程系，马萨诸塞州理工学院，追求博士best-goo敏，生物医学工程系，首尔国立大学，为期24个月，一个合作研究计划的发展计算流体动力学方法，可用于协助设计和优化心脏辅助设备。 美国研究人员带来了他的经验，使用计算方法分析心血管系统中的流动，使用适合于三维，不稳定流动的方法，移动边界的类型发生在人造心脏或心室的腔室。 韩国合作者和他的研究团队为研究带来了他们在全人工心脏开发方面的丰富经验，从设备制造到植入和大型动物的长期测试。 本研究的一个重要组成部分是实验验证和扩展的数值模拟使用激光多普勒测速和粒子图像测速。 这组合作者的综合专业知识将有助于开发可用于设计下一代心脏辅助装置的技术，这些装置可以在流场方面进行优化，以减少血栓形成和溶血的趋势，同时最大限度地降低装置的功率要求。 先前关于植入式心脏辅助装置的研究已经取得了许多成功，但尚未导致可靠的全人工心脏。 该项目的前提是，下一代心脏辅助技术将需要利用新开发的计算方法和实验能力的新工具。 该项目的合作者希望开发这些计算工具。 该项目汇集了韩国生物医学工程和医学专家以及美国计算流体动力学专家。 他们将共同努力开发一种更小、更可靠、更有效的左心室辅助装置。 该项目与美国的目标有关-韩国合作科学计划，旨在通过科学信息，思想，技能和技术的交流以及通过互利问题的合作来提高美国和韩国科学家和工程师之间的合作水平。 该项目为美国研究生提供了国际研究经验。 韩国的参与得到了韩国科学与工程基金会（KOSEF）的支持。 ***

9602180 Kamm This award provides funds to permit Dr. Roger D. Kamm, Department of Mechanical Engineering, Massachusetts Institute of Technology, to pursue with Dr. Byoung-Goo Min, Department of Biomedical Engineering, Seoul National University, for 24 months, a program of cooperative research for the development of computational fluid dynamic methods that can be used to assist in the design and optimization of cardiac assist devices. The U.S. investigator brings his experience with use of computational methods for the analysis of flow in the cardiovascular system, using methods appropriate both for three-dimensional, unsteady flows with moving boundaries of the type that occur in the chambers of the artificial heart or the ventricle. The Korean collaborator and his research team bring to the research their considerable experience in the development of a total artificial heart, extending from fabrication of the device to implantation and long-term testing in large animals. An important component of this research is the experimental verification and extension of the numerical simulations using both laser Doppler anemometry and particle image velocimetry. The combined expertise of this group of collaborators will help in the development of techniques that can be used in the design of the next generation of cardiac assist devices which can be optimized with regard to the flow field to reduce the tendencies for thrombus formation and hemolysis, while minimizing the power requirements of the device. Previous research on implantable heart assist devices has produced many successes, but has not yet lead to a reliable total artificial heart. This project is based on the premise that the next generation of heart assist technology will require new tools that draw upon newly developed capabilities in computational methods and experimentation. The collaborators in this project expect to develop these computational tools. The project brings together Korean experts i n biomedical engineering and medicine and U.S. experts in computational fluid dynamics. Together they will attempt to develop a smaller, more reliable, and more efficient left ventricular assist device. This project is relevant to the objectives of the U.S.-Korea Cooperative Science Program which seeks to increase the level of cooperation between U.S. and Korean scientists and engineers through the exchange of scientific information, ideas, skills, and techniques and through collaboration on problems of mutual benefit. This project provides an international research experience for a U.S. graduate student. Korean participation is supported by the Korea Science and Engineering Foundation (KOSEF). ***