Renovation of Hughes Hall Chemistry Research Facilities

迈阿密大学位于俄亥俄州牛津市，是ARI基金的接受者，用于翻修休斯大厅，这是化学系的所在地。该建筑建于1970年，其系统不足以支持分析、有机化学和生物化学的研究项目。教师目前从事以下研究：利用质谱法探索生物分子的气相化学；傅里叶变换离子回旋共振（FT-ICR）研究多肽和蛋白质离子合成与物理有机化学，植物脂肪酸生物合成途径；电催化，小孢子发生和核-线粒体通讯。目前，现有设施的状况不利于该部研究力量的增长。实验室限制了研究人员进行实验工作的速度，因此也限制了教师的生产力。研究空间不符合现代安全标准，也不适合容纳两个以上的研究学生。该项目将包括改造12个实验室，代表每个目标领域的4个实验室，将现有实验室改造为部门FT-ICR的专用设施，并对一个陈旧的冷室进行现代化改造。除了升级暖通空调、电气和管道设施外，还将安装新的通风柜、实验室操作台和工作台。该项目对化学研究生项目的持续发展至关重要，由于40%的女性参加了该项目，该项目将对未来女性化学家的教育产生一定的影响。

Miami University, located in Oxford Ohio, is the recipient of ARI funds for the renovation of Hughes Hall, home of the Department of Chemistry. Constructed in 1970, the building's systems are inadequate to support research programs in analytical and organic chemistry and biochemistry. Faculty are currently engaged in the following investigations: utilizing mass spectrometry to explore the gas-phase chemistry of biomolecules; Fourier transform ion cyclotron resonance (FT-ICR) studies of peptide and protein ions; synthetic and physical organic chemistry, fatty acid biosynthetic pathways in plants; electrocatalysis, and microsporogenesis and nuclear-mitochondrial communication. The condition of the existing facility is now a detriment to the growth of the Department's research strength. Laboratories limit the rate at which experimental work can be performed by researchers and, therefore, limit the productivity of faculty. Research space does not comply with modern safety standards, nor is it designed to accommodate more than two research students. The project will consist of renovating twelve laboratories, representing four laboratories in each of the targeted fields, converting an exiting laboratory into a dedicated facility for the departmental FT-ICR, and modernizing an antiquated cold room. New fume hoods and laboratory casework and benches, will be installed in addition to upgrading HVAC, electrical and plumbing utilities. This project is critical to the continued development of the graduate program in Chemistry, and since 40% of women are enrolled in the Program, the project will have a definite impact on the education of future women chemists.