Acquisition of a Stopped-Flow UV-Vis Spectrophotometer

在化学研究仪器和设施（CRIF）计划的支持下，迈阿密大学化学系将获得一台止流紫外-可见分光光度计。研究重点将集中在以下方面：a)杂环芳香胺衍生的致癌酯的化学研究；B)水溶液中氧卤素与臭氧的氧化还原反应；C)金属内酰胺酶的动力学机制；d)乙二醛酶的研究。停流光谱对于快速化学反应的研究至关重要，因为它可以检测吸收紫外线或可见光的短寿命中间体。这些研究将对包括环境科学和生物化学在内的各个领域产生影响。

With support from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at Miami University will acquire a stopped-flow UV-VIS spectrophotometer. Research will focus on the following studies: a) chemistry of carcinogenic esters derived from heterocyclic aromatic amines; b) oxidation-reduction reactions of oxyhalogen species and ozone in aqueous solution; c) kinetic mechanism of metallo-beta-lactamases; and d) study of glyoxalase II. Stopped-flow spectroscopy is critical for the study of rapid chemical reactions, as it enables the detection of ultraviolet or visible light-absorbing short-lived intermediates. These studies will have an impact in a variety of areas including environmental sciences and biochemistry.