Acquisition of a Stopped-Flow UV-Vis Spectrophotometer

购买停流紫外可见分光光度计

• 批准号: 0076936
• 负责人: Michael Novak
• 金额: $ 5.34万
• 依托单位: Miami University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-08-01 至 2003-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0076936&HistoricalAwards=false
• 关键词: Acquisition; Stopped; Flow; UV; Vis

With support from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at Miami University will acquire a stopped-flow UV-VIS spectrophotometer. Research will focus on the following studies: a) chemistry of carcinogenic esters derived from heterocyclic aromatic amines; b) oxidation-reduction reactions of oxyhalogen species and ozone in aqueous solution; c) kinetic mechanism of metallo-beta-lactamases; and d) study of glyoxalase II. Stopped-flow spectroscopy is critical for the study of rapid chemical reactions, as it enables the detection of ultraviolet or visible light-absorbing short-lived intermediates. These studies will have an impact in a variety of areas including environmental sciences and biochemistry.

在化学研究仪器和设施（CRIF）计划的支持下，迈阿密大学化学系将获得一台停流紫外可见分光光度计。 研究将侧重于以下研究：a）从杂环芳香胺衍生的致癌酯的化学; B）卤氧物质和臭氧在水溶液中的氧化还原反应; c）金属-β-内酰胺酶的动力学机制; d）甘油二酸酶II的研究。 停流光谱对于快速化学反应的研究至关重要，因为它可以检测吸收紫外或可见光的短寿命中间体。 这些研究将对包括环境科学和生物化学在内的各个领域产生影响。