CONFERENCE: Symposium on Subtypes of Muscarinic Receptors; Vienna, VA, November 12-15, 1996

9603590莱文神经细胞之间的功能性接触被称为突触，在突触的细胞之间传递信号的生物化学化合物被称为神经递质。递质分子被称为受体的分子捕获在靶细胞的细胞膜表面。某些种类的递质，如特定的氨基酸或特定的儿茶酚胺化合物，已知具有特定的受体类型，可以在突触后细胞中触发特定的反应。最近，受体分子的亚型被发现，通常具有不同的化学结合亲和力、分子排列和偶联机制。这次研讨会在分子水平上介绍了在了解称为M受体的特定受体亚型方面的最新进展，M受体调节神经和肌肉细胞对一种名为乙酰胆碱的广泛神经递质的反应。支持是为了帮助支付一些旅行费用，以便该领域的年轻研究人员能够出席这次会议并在会议上发表他们自己的研究成果。这种支持将对促进年轻神经科学家的职业发展产生影响，研讨会演讲将对肌肉和心血管研究以及神经科学产生影响。

9603590 Levin The functional contacts between nerve cells are called synapses, and the biochemical compounds that carry signals between the cells at the synapse are called neurotransmitters. The transmitter molecules are captured on the surface of the cell membrane of the target cell by molecules called receptors. Classes of transmitters, like particular amino acids, or particular catecholamine compounds, were known to have particular receptor types that triggered particular responses in the post-synaptic cell. More recently, subtypes of receptor molecules have been found, often with different chemical binding affinities, molecular arrangement, and coupling mechanisms. This symposium covers recent advances at the molecular level in understanding the subtypes of the particular receptors called muscarinic receptors, which modulate the responses of nerve and muscle cells to a widespread neurotransmitter called acetylcholine. Support is to help cover some travel costs young investigators in the field to be able to attend and deliver their own research results at this meeting. This support will have an impact on fostering the career development of young neuroscientists, and the symposium presentations will have an impact on muscle and cardiovascular research as well as neuroscience.