FASEB Conference: Transcription Initiation in Prokaryotes held on July 19-24, 1997, at the Vermont Academy in Saxtons River, Vermont.

这个项目是为1997年7月19-24日在佛蒙特州萨克斯顿河的佛蒙特学院举行的“原核生物转录起始”的1997年FASEB夏季会议提供部分资金，该会议由美国实验生物学学会联合会（FASEB）主持。将有10个口头会议，平均每个会议有3个30分钟的演讲和2个15分钟的演讲，以及两个海报会议，每次持续两天。会议邀请了32位发言者，并将从提交摘要的与会者中选出另外12位发言者。会议的目的是将生化学家、生物物理学家和遗传学家聚集在一起，分享调控所有细胞中信息流动的关键步骤：转录起始。这一快速发展的领域正在提供分子水平上的结构和机制信息。口头会议将讨论的具体主题是dna依赖的RNA聚合酶的结构，研究转录中蛋白质-蛋白质和蛋白质- dna相互作用的物理和化学方法，启动子识别，古细菌和嗜热细菌的转录起始，转录起始和启动子逃逸的生物化学，阴性和阳性控制的机制，以及复杂系统中转录的控制。＊＊＊

9605206 Rothman-Denes This project is for partial funding for the 1997 FASEB Summer Conference on "Transcription Initiation in Prokaryotes" to be held July 19-24, 1997, at the Vermont Academy in Saxtons River, Vermont, under the auspices of the Federation of American Societies for Experimental Biology (FASEB). There will be ten oral sessions with, on average, three 30 minute talks and two 15 minute talks per session, and two poster sessions, each lasting two days. Thirty-two speakers have been invited and twelve additional speakers will be selected from participants who submitted abstracts. The purpose of the meeting is to bring together biochemists, biophysicists and geneticists to share information on a crucial step that regulates the flow of information in all cells: transcription initiation. The rapidly progressing field is providing information on structure and mechanisms at the molecular level. The specific topics to be discussed in the oral sessions are structure of DNA-dependent RNA polymerases, physical and chemical approaches to study protein-protein and protein-DNA interactions in transcription, promoter recognition, transcription initiation in archae and thermophilic bacteria, biochemistry of transcription initiation and promoter escape, mechanisms of negative and positive control, and control of transcription in complex systems. ***