Conference: FASEB Summer Conference on Prokaryotic Transcription Initiation to be held Summer 2001, at the Vermont Academy in Saxton's River Vermont.

FASE B关于原核转录启动的夏季会议将于2001年7月14-19日在佛蒙特州萨克斯顿河的佛蒙特州学院举行。这次会议将汇集生物化学家、生物物理学家和遗传学家。它将重点放在真细菌上，但将考虑古细菌和真核生物，在这些比较是有趣的。将在2001年FASEB会议上集中研究的领域包括：1.依赖DNA的RNA聚合酶的结构2.西格玛因素和核心互动3。启动子识别和启动。转录激活5。6.复杂的监管。全球监管7.延长复合体的形成和稳定性所有细胞都在几个不同的水平上调节从DNA到蛋白质的信息流。调控的一个主要和最经济的目标是启动转录，通过这个过程，染色体上的基因中的信息以一种小的(相对于染色体的)移动形式编码，供细胞使用。使用易于操纵的细菌系统，科学家们已经发现了许多转录调控的基本原理，并且今天正在探索更多的原理。这次会议将促进对科学研究至关重要的实验结果和思想的自由交流。国家科学基金会提供的资金支持将使学生和博士后研究员能够参加这一重要会议。

The FASEB Summer Conference on Prokaryotic Transcription Initiation will be held July 14-19, 2001, at the Vermont Academy in Saxton's River, Vermont. The meeting will bring together biochemists, biophysicists, and geneticists. It will focus on eubacteria, but there will be consideration of both archaea and eukaryotes where comparison is interesting. Areas of intense study that will be featured at the 2001 FASEB conference include the following:1. Structure of DNA-dependent RNA polymerases2. Sigma factors and core interactions3. Promoter recognition and initiation4. Transcription activation5. Complex regulation6. Global regulation7. Formation and stability of elongation complexesAll cells regulate the flow of information from DNA to protein at several different levels. A primary, and most economical, target of regulation is the initiation of transcription, the process by which the information in a gene on a chromosome is encoded in a small (relative to a chromosome) mobile form for use by the cell. Using easily manipulated bacterial systems, scientists have discovered many fundamental principles of transcriptional regulation and are exploring many more today. This meeting will facilitate the free exchange of experimental results and ideas so essential to this scientific search. The financial support provided by the National Science Foundation will enable students and postdoctoral fellows to attend this important meeting.