Conference: FASEB Summer Conference on Prokaryotic Transcription Initiation to be held Summer 2001, at the Vermont Academy in Saxton's River Vermont.

FASEB夏季会议Proximal转录启动将于2001年7月14日至19日在萨克斯顿河，佛蒙特州佛蒙特学院举行。 会议将汇集生物化学家，生物制药学家和遗传学家。 它将集中在真细菌，但也将考虑古细菌和真核生物的比较是有趣的。 将在2001年FASEB会议上重点介绍的密集研究领域包括：1。DNA依赖性RNA聚合酶的结构2.西格玛因素和核心相互作用3.启动子识别和启动4.转录激活5.复杂的规则6.全球监管7.延伸复合物的形成和稳定性所有细胞都在几个不同的水平上调节从DNA到蛋白质的信息流。一个主要的，也是最经济的调控目标是转录的启动，通过这个过程，染色体上基因中的信息以小的（相对于染色体）移动的形式编码，供细胞使用。 利用易于操作的细菌系统，科学家们已经发现了许多转录调控的基本原则，今天正在探索更多。 这次会议将促进自由交流对这项科学研究至关重要的实验结果和想法。 美国国家科学基金会提供的财政支持将使学生和博士后研究员能够参加这一重要会议。

The FASEB Summer Conference on Prokaryotic Transcription Initiation will be held July 14-19, 2001, at the Vermont Academy in Saxton's River, Vermont. The meeting will bring together biochemists, biophysicists, and geneticists. It will focus on eubacteria, but there will be consideration of both archaea and eukaryotes where comparison is interesting. Areas of intense study that will be featured at the 2001 FASEB conference include the following:1. Structure of DNA-dependent RNA polymerases2. Sigma factors and core interactions3. Promoter recognition and initiation4. Transcription activation5. Complex regulation6. Global regulation7. Formation and stability of elongation complexesAll cells regulate the flow of information from DNA to protein at several different levels. A primary, and most economical, target of regulation is the initiation of transcription, the process by which the information in a gene on a chromosome is encoded in a small (relative to a chromosome) mobile form for use by the cell. Using easily manipulated bacterial systems, scientists have discovered many fundamental principles of transcriptional regulation and are exploring many more today. This meeting will facilitate the free exchange of experimental results and ideas so essential to this scientific search. The financial support provided by the National Science Foundation will enable students and postdoctoral fellows to attend this important meeting.