Organoiron Complexes in Organic Synthesis

这项研究的重点有两个方面。首先，对环辛二烯络合物的化学研究将导致这一重要的碳环体系的立体和区域控制的官能化。其次，将研究铁介导的环羰化α，欧米伽二炔类化合物合成双环(5.3.0)正十二烷的范围。通过这个奖项，合成有机项目支持凯斯西储大学化学系的安东尼·J·皮尔逊博士的研究。皮尔逊教授将专注于研究有机铁化学在构建具有重要生物特性的天然产品方面的应用。

The foci of this research are two-fold. First, the investigation of the chemistry of cyclooctadienyliron complexes will lead to stereo- and regiocontrolled functionalization of this important carbocyclic ring system. Second, the scope of iron-mediated cyclocarbonylation alpha, omega-diynes leading to the construction of bicyclo(5.3.0)decanes will be investigated. With this award, the Synthetic Organic Program is supporting the research of Dr. Anthony J. Pearson of the Department of Chemistry at Case Western Reserve University. Professor Pearson will focus his work on investigating the applications of organoiron chemistry to the construction of natural products having important biological properties.