Development and Applications of Multidimensional NMR Methods in Polymer Science

9617477 Rinaldi在这项资助中，二维和三维核磁共振（NMR）三重技术（在某些情况下连同各向同性标记）被用于研究聚合物结构、聚合物形成和降解机制以及聚合物反应性等问题。多年来在结构生物学中使用的方法正在适应于聚合物科学的应用，并且正在开发独特适用于聚合物研究的新方法。这些方法可以选择性地探测大分子中一小部分发生的结构和转化，而不会受到分子其余部分信号的干扰。这些技术被用于研究聚合物块结的结构，聚合物链的末端和缺陷，以及各种聚合物反应的机理。这些结构的知识为聚合物的形成和稳定性提供了有价值的见解。正在研究的材料对橡胶制品、塑料、半导体和生物医学工程材料的制造具有重要意义。＊＊＊

9617477 Rinaldi In this grant, two- and three-dimensional nuclear magnetic resonance (NMR) triple techniques (together with isotropic labeling in some cases) are being used to study problems in polymer structure, polymer formation and degradation mechanisms, and polymer reactivity. Methods which have been used for years in structural biology are being adapted for application in polymer science and new methods are being developed which are uniquely suited for the study of polymers. These methods allow selective probing of the structure and transformations which occur in one small part of a large molecule without interference from the signals from the rest of the molecule. %%% These techniques are being used to study the structure of polymer block junctions, polymer chain ends and defects, and the mechanisms of various polymer reactions. A knowledge of these structures provides valuable insight into polymer formation and stability. The materials being studied are important for the manufacture of rubber products, plastics, semiconductors, and biomedical engineering materials. ***