Ring Opening Metathesis Polymerization of Imines

匹兹堡大学的Tara Meyer博士将在无机化学、生物无机化学和金属有机化学项目的教职早期职业发展奖的支持下，研究亚胺的开环歧化聚合(ROMP)。应变环亚胺将被聚合，以合成适合用作金属螯合剂和药物载体的聚合物。高价、早熟的金属催化剂将与亚胺单体反应生成聚合物。该项目的教育部分侧重于课程的开发，这些课程包含与现实世界技术问题(如风险评估)相关的复杂思维、决策和解决问题的技能的组合。该项目致力于以一种新的方式利用一种已知的聚合方法合成新的聚合材料。将探索金属化合物和有机单体的基础化学，并可能为新的聚合物材料提供新的途径。这些聚合物在药物输送和从水溶液中去除金属方面具有潜在的应用前景。

Dr. Tara Meyer of the University of Pittsburgh will study ring opening metathesis polymerization (ROMP) of imines with support from a Faculty Early Career Development award in the Inorganic, Bioinorganic, and Organometallic Chemistry Program. Strained-cyclic imines will be polymerized to synthesize polymers suitable for use as metal chelation agents and drug carriers. High-valent, early tranisiton metal catalysts will be reacted with imine monomers to produce the polymers. The education component of this project focuses on the development of courses which encompass a combination of complex thinking, decision making, and problem solving skills that relate to real world technology issues such as risk assessment. This project addresses the synthesis of new, polymeric materials utilizing a known polymerization approach in a novel way. The fundamental chemistry of the metal compounds and organic monomers will be explored, and it is likely to provide new avenues to new polymeric materials. The polymers have potential for applications in drug delivery and metal removal from aqueous solution.