Diverse Degradable Polymers from Versatile Ring-Opening Metathesis (Co)Polymerization of Electron-Rich Cyclic Olefins
富电子环烯烃的多功能开环复分解(共)聚合得到多种可降解聚合物
基本信息
- 批准号:2106511
- 负责人:
- 金额:$ 60万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Continuing Grant
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-09-01 至 2025-08-31
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
With the support of the Macromolecular, Supramolecular and Nanochemistry Program in the Division of Chemistry, Professor Yan Xia of Stanford University will develop new chemistry for generating new types of degradable plastics to address the grand end-of-life challenge of persistent plastics to the environment and human health. In 2018, 27 million tons of plastics were landfilled or released into the environment in the US and are nondegradable. New polymers that are strategically designed to be recycled, degraded, or depolymerized on demand are highly desirable for environmental sustainability as well as many technological and biomedical applications. This project integrates educational endeavors at several levels to raise the public awareness of plastic pollution and recycling, and recruit and cultivate pre-college students, especially underrepresented students in the Bay Area, for future STEM careers. The research also provides perfect examples to interface organic chemistry, polymer science, and sustainability in undergraduate and graduate curriculum.Ring-opening metathesis polymerization (ROMP) of cyclic alkenes is a widely used method to synthesize controlled functional polymers. Enol ethers with an electron-rich alkene have long been believed to deactivate the catalysts for ROMP and routinely used to quench the polymerization. But the Xia laboratory discovered surprisingly efficient ROMP of cyclic enol ethers and their copolymerization with strained cyclic alkenes, leading to new types of degradable polymers with acid labile backbones. This research project will explore the metathesis chemistry of electron-rich heteroatom-substituted cyclic alkenes and their copolymerization for the first time, and understand how the thermodynamic and kinetic parameters impact the control, microstructures, degradation profiles, and physical properties of the resulting degradable/depolymerizable polymers.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
在化学系大分子、超分子和纳米化学项目的支持下,斯坦福大学的夏岩教授将开发新的化学,以产生新型可降解塑料,以应对持久性塑料对环境和人类健康的重大生命周期挑战。2018年,美国有2700万吨塑料被填埋或排放到环境中,这些塑料是不可降解的。可按需回收、降解或解聚的新型聚合物在环境可持续性以及许多技术和生物医学应用方面都是非常理想的。该项目整合了多个层面的教育努力,以提高公众对塑料污染和回收的意识,并招收和培养大学预科学生,特别是湾区代表不足的学生,为未来的STEM职业生涯做准备。这项研究也为本科生和研究生课程中有机化学、聚合物科学和可持续性的结合提供了完美的范例。环烯烃开环歧化聚合(ROMP)是一种广泛使用的合成可控功能聚合物的方法。长期以来,人们一直认为含有富含电子的烯烃的烯醇醚会使ROMP的催化剂失活,并经常用于冷却聚合。但夏实验室发现了令人惊讶的高效环烯醇醚及其与应变环烯烃的共聚,导致了新型具有不稳定酸主链的可降解聚合物。这项研究项目将首次探索富含电子的杂原子取代的环烯及其共聚的歧化化学,并了解热力学和动力学参数如何影响所产生的可降解/可解聚聚合物的控制、微观结构、降解特征和物理性质。该奖项反映了NSF的法定使命,并通过使用基金会的智力优势和更广泛的影响审查标准进行评估,被认为值得支持。
项目成果
期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
A versatile approach for the synthesis of degradable polymers via controlled ring-opening metathesis copolymerization
- DOI:10.1038/s41557-021-00810-2
- 发表时间:2021-11-18
- 期刊:
- 影响因子:21.8
- 作者:Feist, John D.;Lee, Daniel C.;Xia, Yan
- 通讯作者:Xia, Yan
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Yan Xia其他文献
O-GlcNAcylation of cardiac Nav1.5 contributes to the development of arrhythmias in diabetic hearts
心脏 Nav1.5 的 O-GlcNAc 酰化导致糖尿病心脏心律失常的发生
- DOI:
10.1016/j.ijcard.2018.02.099 - 发表时间:
2018 - 期刊:
- 影响因子:3.5
- 作者:
Yu Peng;Hu Lili;Xie Jinyan;Chen Sisi;Huang Lin;Xu Zixuan;Liu Xiao;Zhou Qiongqiong;Yuan Ping;Yan Xia;Jin Jiejin;Shen Yang;Zhu Wengen;Fu Linghua;Chen Qi;Yu Jianhua;Hu Jianxin;Cao Qing;Wan Rong;Hong Kui - 通讯作者:
Hong Kui
On the quantitative relationship of the in-cylinder heat to work conversion process of natural gas spark ignited engine under steady state and transient operation conditions
天然气火花点火发动机稳态和瞬态工况缸内热功转换过程的定量关系
- DOI:
10.1016/j.energy.2020.119607 - 发表时间:
2021-04 - 期刊:
- 影响因子:9
- 作者:
Yan Xia;Yangyang Li;Cheng Liao;Jingping Liu;Shuqian Wang;Junhao Qiao;Shijia Zhang - 通讯作者:
Shijia Zhang
2D Heterostructure of Bi2O2Se/Bi2SeOx Nanosheet for Resistive Random Access Memory
用于电阻式随机存取存储器的 Bi2O2Se/Bi2SeOx 纳米片的二维异质结构
- DOI:
10.1002/aelm.202200126 - 发表时间:
2022-09 - 期刊:
- 影响因子:6.2
- 作者:
Yan Xia;Jing Wang;Rui Chen;Hongbo Wang;Hang Xu;Changzhong Jiang;Wenqing Li;Xiangheng Xiao - 通讯作者:
Xiangheng Xiao
Gradual Gradient Two-Dimensional Preparative Liquid Chromatography System for Preparative Separation of Complex Natural Products
用于制备分离复杂天然产物的渐进梯度二维制备液相色谱系统
- DOI:
10.1007/s10337-018-3652-8 - 发表时间:
2018-11 - 期刊:
- 影响因子:1.7
- 作者:
Wang Zheng;Xie Ting Ting;Yan Xia;Xue Shi;Chen Jing Wei;Wu Zhen;Qiu Ying Kun - 通讯作者:
Qiu Ying Kun
Improved modelling of interfacial terms in the second-moment closure for particle-laden flows based on interface-resolved simulation data
基于界面解析模拟数据改进颗粒负载流二阶矩闭合中界面项的建模
- DOI:
10.1017/jfm.2022.927 - 发表时间:
2022-11 - 期刊:
- 影响因子:3.7
- 作者:
Yan Xia;Zhaosheng Yu;Zhaowu Lin;Yu Guo - 通讯作者:
Yu Guo
Yan Xia的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Yan Xia', 18)}}的其他基金
Probing and Designing Cascade Reactivity in Consecutive Mechanoactivation of Covalent Bonds
共价键连续机械活化中的级联反应性的探索和设计
- 批准号:
2350170 - 财政年份:2024
- 资助金额:
$ 60万 - 项目类别:
Standard Grant
I-Corps: Green Manufacturing of Recyclable High-Performance Composites
I-Corps:可回收高性能复合材料的绿色制造
- 批准号:
2230789 - 财政年份:2022
- 资助金额:
$ 60万 - 项目类别:
Standard Grant
Conjugated Systems Containing Antiaromatic Cyclobutadienoids: Synthesis and Study of the Multifaceted Effects of Local Antiaromaticity
含有抗芳香环丁二烯类化合物的共轭体系:局部抗芳香性多方面效应的合成和研究
- 批准号:
1855922 - 财政年份:2019
- 资助金额:
$ 60万 - 项目类别:
Standard Grant
Project Description: United States-Japan Polymer Symposium: Macromolecules: "Challenges and Opportunities for the 21st Century"
项目简介:美日聚合物研讨会:高分子:“21世纪的挑战与机遇”
- 批准号:
1919521 - 财政年份:2019
- 资助金额:
$ 60万 - 项目类别:
Standard Grant
CAREER: Controlling Polymer Degradation, Microstructures, and Sequences via Living Alternating Polymerization of Cyclopropenes and Low-Strain Cyclic Olefins
职业:通过环丙烯和低应变环烯烃的活性交替聚合来控制聚合物降解、微观结构和序列
- 批准号:
1553780 - 财政年份:2016
- 资助金额:
$ 60万 - 项目类别:
Continuing Grant
相似海外基金
CAREER: CAS: Copolymerization of Vinyl Monomers with Isocyanides for Degradable Polymers
职业:CAS:乙烯基单体与异氰化物共聚制备可降解聚合物
- 批准号:
2237784 - 财政年份:2023
- 资助金额:
$ 60万 - 项目类别:
Continuing Grant
Synthesis of easily degradable vinyl polymers by "Reversed-Depolymerization"
通过“反向解聚”合成易降解乙烯基聚合物
- 批准号:
23KJ1042 - 财政年份:2023
- 资助金额:
$ 60万 - 项目类别:
Grant-in-Aid for JSPS Fellows
CAREER: Synthesis and Application of Bioorthogonally Degradable Polymers
职业:生物正交降解聚合物的合成及应用
- 批准号:
2238040 - 财政年份:2023
- 资助金额:
$ 60万 - 项目类别:
Continuing Grant
LEAPS-MPS: Biomass-Derived Depolymerizable and Degradable Polymers as Sustainable Materials
LEAPS-MPS:生物质衍生的可解聚和可降解聚合物作为可持续材料
- 批准号:
2316842 - 财政年份:2023
- 资助金额:
$ 60万 - 项目类别:
Standard Grant
CAREER: CAS: Copolymerization of Vinyl Monomers with Isocyanides for Degradable Polymers
职业:CAS:乙烯基单体与异氰化物共聚制备可降解聚合物
- 批准号:
2337228 - 财政年份:2023
- 资助金额:
$ 60万 - 项目类别:
Continuing Grant
ECO-CBET: A Convergent Approach to the Rational Design of Controllably Degradable Polymers using Sustainable Nanocomposites and Biodegradable-Additives
ECO-CBET:使用可持续纳米复合材料和生物可降解添加剂合理设计可控降解聚合物的收敛方法
- 批准号:
2318652 - 财政年份:2023
- 资助金额:
$ 60万 - 项目类别:
Standard Grant
Insights into Degradable Branched Step-growth Polymers using Transfer-dominated Branching Radical Telomerisation
使用转移主导的支化自由基调聚对可降解支化逐步增长聚合物的见解
- 批准号:
EP/X010864/1 - 财政年份:2023
- 资助金额:
$ 60万 - 项目类别:
Research Grant
New Designs for Degradable Polymers
可降解聚合物的新设计
- 批准号:
RGPIN-2021-03950 - 财政年份:2022
- 资助金额:
$ 60万 - 项目类别:
Discovery Grants Program - Individual
Development of bio-degradable and bio-based polymers
生物可降解和生物基聚合物的开发
- 批准号:
574376-2022 - 财政年份:2022
- 资助金额:
$ 60万 - 项目类别:
University Undergraduate Student Research Awards
Synthesis of Bioderived and Degradable Semiconducting Polymers for Electronic Devices
用于电子设备的生物源可降解半导体聚合物的合成
- 批准号:
569206-2022 - 财政年份:2022
- 资助金额:
$ 60万 - 项目类别:
Alexander Graham Bell Canada Graduate Scholarships - Doctoral














{{item.name}}会员




