Diverse Degradable Polymers from Versatile Ring-Opening Metathesis (Co)Polymerization of Electron-Rich Cyclic Olefins

富电子环烯烃的多功能开环复分解(共)聚合得到多种可降解聚合物

基本信息

  • 批准号:
    2106511
  • 负责人:
  • 金额:
    $ 60万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Continuing Grant
  • 财政年份:
    2021
  • 资助国家:
    美国
  • 起止时间:
    2021-09-01 至 2025-08-31
  • 项目状态:
    未结题

项目摘要

With the support of the Macromolecular, Supramolecular and Nanochemistry Program in the Division of Chemistry, Professor Yan Xia of Stanford University will develop new chemistry for generating new types of degradable plastics to address the grand end-of-life challenge of persistent plastics to the environment and human health. In 2018, 27 million tons of plastics were landfilled or released into the environment in the US and are nondegradable. New polymers that are strategically designed to be recycled, degraded, or depolymerized on demand are highly desirable for environmental sustainability as well as many technological and biomedical applications. This project integrates educational endeavors at several levels to raise the public awareness of plastic pollution and recycling, and recruit and cultivate pre-college students, especially underrepresented students in the Bay Area, for future STEM careers. The research also provides perfect examples to interface organic chemistry, polymer science, and sustainability in undergraduate and graduate curriculum.Ring-opening metathesis polymerization (ROMP) of cyclic alkenes is a widely used method to synthesize controlled functional polymers. Enol ethers with an electron-rich alkene have long been believed to deactivate the catalysts for ROMP and routinely used to quench the polymerization. But the Xia laboratory discovered surprisingly efficient ROMP of cyclic enol ethers and their copolymerization with strained cyclic alkenes, leading to new types of degradable polymers with acid labile backbones. This research project will explore the metathesis chemistry of electron-rich heteroatom-substituted cyclic alkenes and their copolymerization for the first time, and understand how the thermodynamic and kinetic parameters impact the control, microstructures, degradation profiles, and physical properties of the resulting degradable/depolymerizable polymers.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
在化学系高分子、超分子和纳米化学项目的支持下,斯坦福大学的严夏教授将开发新的化学方法,用于生产新型可降解塑料,以应对持久性塑料对环境和人类健康的巨大挑战。2018年,美国有2700万吨塑料被填埋或释放到环境中,并且不可降解。战略性地设计为可按需回收、降解或解聚的新聚合物对于环境可持续性以及许多技术和生物医学应用是非常理想的。该项目整合了多个层面的教育努力,以提高公众对塑料污染和回收的认识,并招募和培养大学预科生,特别是湾区代表性不足的学生,为未来的STEM职业生涯。本研究也为有机化学、高分子科学和可持续发展在本科和研究生课程中的衔接提供了完美的范例。环烯烃开环易位聚合(ROMP)是一种广泛应用的合成可控功能聚合物的方法。具有富电子烯烃的烯醇醚长期以来被认为使用于ROMP的催化剂失活并且常规地用于淬灭聚合。但是Xia实验室发现了令人惊讶的有效的环烯醇醚的ROMP及其与应变环烯烃的共聚,导致具有酸不稳定主链的新型可降解聚合物。该研究项目将首次探索富电子杂原子取代环烯烃的复分解化学及其共聚反应,并了解热力学和动力学参数如何影响控制,微观结构,降解曲线,和所得可降解/该奖项反映了NSF的法定使命,并已被认为是值得通过使用基金会的评估支持。知识价值和更广泛的影响审查标准。

项目成果

期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
A versatile approach for the synthesis of degradable polymers via controlled ring-opening metathesis copolymerization
  • DOI:
    10.1038/s41557-021-00810-2
  • 发表时间:
    2021-11-18
  • 期刊:
  • 影响因子:
    21.8
  • 作者:
    Feist, John D.;Lee, Daniel C.;Xia, Yan
  • 通讯作者:
    Xia, Yan
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Yan Xia其他文献

Study on isolating Matsutake mycorrhizas-associated actinobacteria and evaluating their impacts on fungal growth
松茸菌根相关放线菌的分离及其对真菌生长影响的研究
  • DOI:
    10.11519/jfsc.128.0_505
  • 发表时间:
    2017
  • 期刊:
  • 影响因子:
    0
  • 作者:
    C. Lian;Yan Xia;Jian Huang;Hiroyuki Kurokuchi;N. Matsushita;Y. Ota;P. Pawara;Shijie Zhang;Lu
  • 通讯作者:
    Lu
Remarkable Protective Effects of Nrf2-Mediated Antioxidant Enzymes and Tissue Specificity in Different Skeletal Muscles of Daurian Ground Squirrels Over the Torpor-Arousal Cycle
Nrf2介导的抗氧化酶对达斡尔地松鼠不同骨骼肌的显着保护作用和组织特异性对麻木-觉醒周期的影响
  • DOI:
    10.3389/fphys.2019.01449
  • 发表时间:
    2019-11
  • 期刊:
  • 影响因子:
    4
  • 作者:
    Wei Yanhong;Zhang Jie;Yan Xia;Peng Xin;Xu Shenhui;Chang Hui;Wang Huiping;Gao Yunfang
  • 通讯作者:
    Gao Yunfang
Complete Bell-state analysis for superconducting-quantum-interference-device qubits with a transitionless tracking algorithm
使用无过渡跟踪算法对超导量子干涉装置量子位进行完整的贝尔态分析
  • DOI:
    10.1103/physreva.96.022304
  • 发表时间:
    2017-07
  • 期刊:
  • 影响因子:
    2.9
  • 作者:
    Yi-Hao Kang;Ye-Hong Chen;Zhi-Cheng Shi;Bi-Hua Huang;Jie Song;Yan Xia
  • 通讯作者:
    Yan Xia
Theoretical analysis of fracture conductivity created by the channel fracturing technique
河道压裂技术裂缝导流能力理论分析
Studies on structural, electrical and magnetic properties of Dy-doped BiFeO3 thin films
Dy掺杂BiFeO3薄膜的结构、电学和磁学性能研究

Yan Xia的其他文献

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{{ truncateString('Yan Xia', 18)}}的其他基金

Probing and Designing Cascade Reactivity in Consecutive Mechanoactivation of Covalent Bonds
共价键连续机械活化中的级联反应性的探索和设计
  • 批准号:
    2350170
  • 财政年份:
    2024
  • 资助金额:
    $ 60万
  • 项目类别:
    Standard Grant
I-Corps: Green Manufacturing of Recyclable High-Performance Composites
I-Corps:可回收高性能复合材料的绿色制造
  • 批准号:
    2230789
  • 财政年份:
    2022
  • 资助金额:
    $ 60万
  • 项目类别:
    Standard Grant
Conjugated Systems Containing Antiaromatic Cyclobutadienoids: Synthesis and Study of the Multifaceted Effects of Local Antiaromaticity
含有抗芳香环丁二烯类化合物的共轭体系:局部抗芳香性多方面效应的合成和研究
  • 批准号:
    1855922
  • 财政年份:
    2019
  • 资助金额:
    $ 60万
  • 项目类别:
    Standard Grant
Project Description: United States-Japan Polymer Symposium: Macromolecules: "Challenges and Opportunities for the 21st Century"
项目简介:美日聚合物研讨会:高分子:“21世纪的挑战与机遇”
  • 批准号:
    1919521
  • 财政年份:
    2019
  • 资助金额:
    $ 60万
  • 项目类别:
    Standard Grant
CAREER: Controlling Polymer Degradation, Microstructures, and Sequences via Living Alternating Polymerization of Cyclopropenes and Low-Strain Cyclic Olefins
职业:通过环丙烯和低应变环烯烃的活性交替聚合来控制聚合物降解、微观结构和序列
  • 批准号:
    1553780
  • 财政年份:
    2016
  • 资助金额:
    $ 60万
  • 项目类别:
    Continuing Grant

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