CAREER: An Integrated Career Development Plan: Enhanced Molecular Transport Across Lipid Bilayer Membranes
CAREER: An Integrated Career Development Plan: Enhanced Molecular Transport Across Lipid Bilayer Membranes
批准号:
9624832
负责人:
Mark Prausnitz
金额:
$32.5万
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
1996
资助国家:
美国
项目状态:
已结题
起止时间:
1996-07-01 至 2001-06-30
中文摘要
9624832 Prausnitz这个职业发展计划包括研究和教育活动。该研究的目的是发展对超声在跨脂质双分子层膜上的分子运输作用的机制理解,特别是在药物输送应用方面。流式细胞术、荧光显微镜和阻抗显微镜将用于评估运输速率和测试各种运输机制的存在。这项研究还将调查超声波对增加分子在皮肤上的转运率的影响。该教育计划的目标是扩大学生与不同学科的其他科学家互动的社区。其中一些方面包括在标准化学工程课程中使用非传统问题,以及开发新的生物工程课程,强调跨学科思考和与校外人员的互动。***
英文摘要
9624832 Prausnitz This career development plan contains both research and education activities. The objective of the research is to develop a mechanistic understanding of the effects of ultrasound on molecular transport cross lipid bilayer membranes, with particular regard to drug delivery applications. Flow cytometry, fluorescence microscopy, and impedance microscopy will be used to assess transport rates and test for the presence of various transport mechanisms. This research will also investigate the effect of ultrasound on increasing molecular transport rates across skin. The goal of the educational plan is to broaden the community in which students interact with other scientists in various disciplines. Some aspects of this include the use of nontraditional problems in standard chemical engineering courses, and the development of a new bioengineering course which emphasizes cross- disciplinary thinking and interaction with people outside the university. ***
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会议论文
UNS: Intracellular Drug Delivery Mediated by Laser-activated Nanoparticles
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批准号:1510028
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项目类别:Standard Grant
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资助金额:$32.9万
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财政年份:2015
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负责人:Mark Prausnitz
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依托单位:
Controlled Cavitation for Ultrasound-Mediated Drug Delivery
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批准号:9987698
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项目类别:Standard Grant
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资助金额:$29.01万
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财政年份:2000
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负责人:Mark Prausnitz
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依托单位:
SGER: Microfabricated Microneedles: Feasibility Studies of Transdermal Insulin Delivery
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批准号:9813321
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项目类别:Standard Grant
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资助金额:$10.0万
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财政年份:1998
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负责人:Mark Prausnitz
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依托单位:
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