SBIR PHASE II: The Development of a 600 MHz Wide Bore (89 mm) High Resolution NMR Magnet with Internal Tin Wires

本小企业创新研究二期项目是研制600MHz宽孔径（89mm）高分辨率核磁共振磁体样机，内部有锡超导导线。该方法的可行性已在一期试验中得到充分证明。通过用内部锡线代替青铜加工线，将显著降低高场核磁共振系统成本。第二阶段的研究目标是建立、测试和评估所提出的全尺寸原型核磁共振磁体。为了实现这一目标，cryomigtics公司提出了一种技术方法，即在持续模式下分别测试每个NbTi和Nb3Sn线圈的稳定性，以确保每个线圈的性能，然后组装线圈并测试磁体。在第二阶段研究结束时，将开发一个全尺寸原型600 MHz宽孔高分辨率核磁共振磁体并进行全面测试。这个原型磁铁将成为第三阶段项目的卖点——600兆赫宽口径高分辨率核磁共振磁铁的商业化。一期和二期开发的新技术将通过降低核磁共振系统成本产生巨大的商业影响。所提出的大口径核磁共振磁体系统将是微成像和体内光谱以及生物固态核磁共振光谱的理想选择。该项目二期的成功完成将使廉价、宽口径、高场核磁共振磁体进入市场。＊＊＊

*** 9704131 Wu This Small Business Innovation Research Phase II project is to develop a prototype 600MHz wide bore (89mm) high resolution NMR magnet with internal tin superconducting wires. The feasibility of this approach has been fully proven in Phase I. Through replacement of bronze-processed wire by internal tin wire, high field NMR system cost will be reduced significantly. The Phase II research objective is to build, test and evaluate the proposed full scale prototype NMR magnet. To achieve the objectives, Cryomagnetics, Inc. proposes a technical approach consisting of testing stability of each NbTi and Nb3Sn coil separately under persistent mode operation to insure each coil's performance, and then assembling coils and testing the magnet. At the end of Phase II research, a full scale prototype 600 MHz wide bore high resolution NMR magnet will be developed and fully tested. This prototype magnet will be the selling point for the Phase III program--the commercialization of 600 MHz wide bore high resolution NMR magnets. The new technologies developed in Phase I and II will generate great commercial impact by reducing NMR system cost. The proposed wide bore NMR magnet system will be ideal for micro-imaging and in vivo spectroscopy as well as biological solid state NMR spectroscopy. The successful completion of Phase II of this project will make inexpensive, wide bore, high field NMR magnets available in the market. ***