US-Japan Joint Seminar: Proton-Coupled Electron Transfer

小行星9726635 该奖项支持美国科学家和工程师参与美国-日本质子耦合电子转移研讨会，拟于1998年11月11日至15日在夏威夷科纳举行。 共同组织者是密歇根州立大学的Gerald Babcock教授和日本冈崎国立研究所的Teizo Kitagawa教授。 最近在这一领域取得了迅速进展。 解出了细菌反应中心、细胞色素氧化酶和细胞色素bc 1复合物的x射线晶体结构。 重要的结构工作来自使用共振拉曼红外和电子顺磁共振光谱的研究。 此外，质子耦合到电子转移和质子转移到电子转移位点的途径的模型已经提出，并通过动力学测量，定点诱变，理论计算和其他方法进行了测试。 讨论将集中在这些模型上。 这一领域的研究在光合作用和呼吸作用中有重要的应用;光系统II中的氧释放和细胞色素c氧化酶中的氧还原，细菌反应中心中的醌还原和细胞色素bc 1复合物中的醌反应。 与日本专家在这一领域的想法和数据交流将使美国参与者能够推进自己的工作，并为未来的合作项目奠定基础。 研讨会的组织者作出了特别的努力，使研究人员，包括博士后研究人员和研究生的混合。 会议记录预计将由组织者提供。 ***

9726635 Babcock This award supports the participation of American scientists and engineers in a U.S.-Japan seminar on proton-coupled electron transfer, to be held in Kona, Hawaii, November 11- 15, 1998. The co-organizers are Professor Gerald Babcock of Michigan State University and Professor Teizo Kitagawa of the Okazaki National Research Institute in Japan. Recent rapid advances have been made in this area. The x-ray crystal structures of the bacterial reaction center, the cytochrome oxidase and the cytochrome bc1 complex have been solved. Important structural work has come from studies using resonance raman infrared and electron paramagnetic resonance spectroscopy. In addition models for proton coupling to electron transfer and pathways for proton transfer into the electron transfer site have been presented and tested by kinetic measurements, site directed mutagenesis, theoretical calculations and other methods. Discussions will focus on these models. This area of research has important applications in photosynthesis and respiration; oxygen evolution in photosystem II and oxygen reduction in cytochrome c oxidase, quinone reduction in bacterial reaction centers and quinone reactions in the cytochrome bc1 complex. The exchange of ideas and data with Japanese experts in this field will enable U.S. participants to advance their own work, and will set the stage for future collaborative projects. Seminar organizers have made a special effort to involve a mix of researchers, including postdoctoral researchers and graduate students. Proceedings of the meeting are expected to be made available by the organizers. ***