Laboratories in Biomolecular and Cellular Engineering

在分子和细胞生物学进步的刺激下，生物医学工程中一个新的和不断发展的研究活动是在双分子，细胞和组织水平上的工程应用。这项研究的总体目标是生产天然或修饰的治疗生物分子和杂交组织和器官的设计。由于这一发展活动的重要性，本提案的目标是将生物分子，细胞和组织工程纳入本科课程。我们建议通过修改和扩大生物医学工程三门必修课程和两门选修课的实验室组成部分来实现这一目标，并为这一领域的独立学习课程提供更多的机会。 实验项目将通过直接展示基本概念和说明相关的生物医学实例以及使用现代仪器和技术的材料应用来补充课程材料。该设备也将可用于本科生独立学习研究。配套资金将由杜克大学工程学院和生物医学工程系提供。此外，其中一名共同研究者将致力于增加独立研究中代表性不足的群体的存在。该项目的共同研究者教授的课程将被修订，并监督本科生在双分子，细胞和组织工程方面的独立研究。

Stimulated by advances in molecular and cellular biology, a new and evolving research activity within biomedical engineering is the application of engineering at the bimolecular, cellular and tissue levels. The overall goal of this research is to produce natural or modified therapeutic biomolecules and the design of hybrid tissues and organs. As a result of the importance of this developing activity, the objective of this proposal is to integrate biomolecular, cellular and tissue engineering into the undergraduate curriculum. We propose to achieve this objective by modifying and expanding the laboratory component of three required courses in biomedical engineering and two electives and to provide increased opportunities for independent study coursework in this area. Laboratory projects will complement class material by directly demonstrating fundamental concepts and illustrating relevant biomedical examples and applications of the material using modern instrumentation and techniques. This equipment will also be available for use in undergraduate independent study research. Matching funds will be provided by the School of Engineering and the Department of Biomedical Engineering at Duke University. Additionally, one of the Co-investigators will work to increase the presence of underrepresented groups in independent study research. Co-investigators on this project teach the courses which will be revised and supervise independent study research by undergraduates in bimolecular, cellular and tissue engineering.