Dissertation Research: Roots, Genes, and Sciences: Re-Visioning Sickle Cell Knowledge in Dakar

拟议的论文研究文件之间的巴黎和达喀尔的镰状细胞病知识的流动。塞内加尔镰状细胞贫血的条件和限制促使达喀尔Fann地区Hopital Albert Royer的法国培训医生质疑美国和法国建立的镰状细胞患者护理和治疗方案的普遍性。已知大西洋非洲的镰状细胞病与一种特定的遗传变异（塞内加尔单倍型）相对应，这可能是造成这种疾病不太严重的原因。该项目认真对待文化和生物学之间的辩证关系，追踪生物学差异、地理和文化价值观如何有助于科学和医学知识的改变。通过基于访谈和参与观察的解释性社会科学方法，研究人员将分析动态过程，从而重新思考塞内加尔和其他地方的镰状细胞护理方法。

The proposed dissertation research documents the flow of sickle cell disease knowledge between Paris and Dakar. The conditions and constraints of sickle cell anemia in Senegal have prompted French-trained physicians at the Hopital Albert Royer in the Fann area of Dakar to question the universality of sickle cell patient care and treatment protocols as these have been established in the United States and France. Sickle cell disease in Atlantic Africa is known to correspond with a specific genetic variant (the Senegalese haplotype) which may be responsible for a less severe form of this disease. This project takes seriously a dialectic between culture and biology, by tracing the ways in which biological difference, geography and cultural values contribute to the modification of scientific and medical knowledge. Through interpretive social science methods based on interviews and participant-observation, the investigator will analyze the dynamic processes that allow for rethinking approaches to sickle cell care in Senegal and elsewhere.