Synthesis and Chemistry of Theoretically Interesting Fluorocarbons

本研究的重点是制备和研究一系列高应变碳氟化合物和碳氟化合物结合有趣的共轭体系的性质。 该项目包括合成用于构建全氟轮烯和价异构体的结构单元，以及合成新的光化学源二氟卡宾。有了这个更新奖，有机和大分子化学计划支持博士的研究。大卫M。达特茅斯学院化学系的勒梅尔说。 Lemal教授将把工作重点放在扩展氟碳化合物结构，反应性和合成的现有知识上，并深入了解将氟碳化合物与碳氢化合物类似物区分开来的特征。 氟碳化合物及其衍生材料在我们的社会中有着广泛的应用，从高温、化学惰性聚合物到表面活性剂，从制冷剂到血液替代品，再到吸入麻醉剂。 该项目将为一些本科生和研究生提供合成和物理有机方法方面的培训。

The focus of this research is the preparation and study of the properties of an array of highly strained fluorocarbons and fluorocarbons incorporating interesting conjugated systems. The project includes synthesis of a building block for use in the construction of perfluoroannulenes and valence isomers, as well as synthesis of a new photochemical source of difluorcarbene.With this renewal award, the Organic and Macromolecular Chemistry Program is supporting the research of Dr. David M. Lemal of the Department of Chemistry at Dartmouth College. Professor Lemal will focus his work on extending current knowledge of fluorocarbon structure, reactivity, and synthesis, and on gaining a deeper understanding of those features that distinguish fluorocarbons from hydrocarbon analogs. Fluorocarbons and derived materials have found a tremendous range of applications in our society ranging from high-temperature, chemically inert polymers to surfactants to refrigerants to blood substitutes to inhalation anaesthetics. The project will provide training in synthetic and physical organic methods for a number of undergraduates and graduate students.