Postdoctoral Research Fellowship in Biological Informatics for FY 2000

这项行动为2000年NSF生物信息学博士后研究奖学金提供资金。研究和培训计划是在生态和进化生理学领域，是分析宿主-寄生虫特征进化的系统发育比较方法”。该提案的目的是开发比较方法，以测试相关的演变。 以往的宿主-寄生虫进化的调查提供了主机和寄生虫的系统发育树的一致性的分析，但未能表征和描述性状进化的相关/因果关系的影响。 本研究的目的是1。利用计算机模拟技术，确定不同水平的寄主-寄生树一致性对性状进化比较研究的统计结果。开发一个系统，最大限度地减少统计偏差和不一致时，主机寄生树不完全一致，和3。将这些方法应用于真实世界的数据集，以测试灵长类和食肉动物中宿主-寄生虫性状进化的假设。 这项研究将大大有助于进化论的知识。

This action funds an NSF Postdoctoral Research Fellowship in Biological Informatics for 2000.The research and training plan is in the area of Ecological and Evolutionary Physiology and is Phylogenetic Comparative Methods to Analyze Host-Parasite Trait Evolution". The aim of this proposal is to develop comparative methods to test for correlated evolution. Previous investigations of host-parasite evolution have provided analyses of the congruence of the phylogenetic trees of hosts and parasites, yet have failed to characterize and describe correlative/causal effects on trait evolution. The aims of this research are 1. To use simulation techniques to identify the statistical consequences of different levels of host-parasite tree congruence on comparative studies of trait evolution, via computer simulation 2. Develop a system that minimizes statistical bias and inconsistency when host-parasite trees are not fully congruent, and 3. Apply these methods to real-world datasets to test hypotheses for host-parasite trait evolution in primates and carnivores. This research will contribute greatly to knowledge of evolution.