Conference on 'Ribosome Biogenesis and Nucleolar Function' to be held August 17-21, 2000, at the Granlibakken Conference Center in Tahoe, California

摘要MCB-0077577Lindahl和Zengel核糖体生物发生和核仁功能会议(计划于2000年8月17-21日在加利福尼亚州塔霍市举行)是一系列三年一次的会议中的第五次。这些会议的目的是让该领域的工作者，包括博士后和学生，对涉及核糖体生物发生的所有方面的研究有一个最新的看法。核糖体对从细菌到人类的所有有机体的生存都是必不可少的。核糖体的形成需要一系列复杂但高度协调的反应，包括转录、翻译、剪接、RNA加工、核糖体成分和组装的前体核糖体颗粒的运输以及RNA和蛋白质的修饰。对这一系列广泛的反应的研究，共同完成了新核糖体的生物发生，需要许多类型的专业知识，包括酶学、遗传学、细胞学和超微分析。没有一个实验室可以拥有所有这些类型的专业知识，但每个研究核糖体生物发生方面的工作人员都应该了解所有其他领域的进展。这次会议汇集了研究各种生物体中核糖体合成方方面面的研究人员，从真细菌到人类。

AbstractMCB-0077577Lindahl and ZengelThe Ribosome Biogenesis and Nucleolar Function meeting (planned for August 17-21, 2000 in Tahoe, CA), is the fifth in a series of tri-annual meetings. The purpose of these meetings is to give workers in the field, including post-docs and students, an up-to-date view of research addressing all aspects of ribosome biogenesis. Ribosomes are essential to survival of all organisms, from bacteria to humans. The formation of ribosomes requires a complicated, but highly coordinated, set of reactions, including transcription, translation, splicing, RNA processing, trafficking of ribosomal components and assembled precursor ribosomal particles, and RNA and protein modifications. The investigation of this extensive suite of reactions, which collectively accomplish the biogenesis of new ribosomes, requires many types of expertise, including enzymology, genetics, cytology and ultramicroscopic analysis. No single lab can possess all of these types of expertise, yet every worker investigating an aspect of ribosome biogenesis should understand the progress in all other areas. The meeting brings together researchers working on all aspects of ribosome synthesis in a variety of organisms, from eubacteria through humans.