Acquisition of a Microarray Facility

加州大学洛杉矶分校(UCLA)健康科学中心(CHS)的分子和医学药理学(DMMP)系将启动一个综合微阵列设施。该设施将由一个DNA处理机器人、一个微阵列、一个扫描仪、一个DNA/克隆资源和一个计算设施组成。微阵列设备的设计旨在提供这项强大技术的最高可行吞吐量。研究将涵盖现代生物学的全部范围，包括逆转录病毒、神经干细胞和其他细胞的分化、细胞对金属的反应、突触传递、神经生长因子、一氧化二氮生理学、免疫系统分化、神经行为方面和糖皮质激素信号。一个重要的部分是利用该设施提供的数据来改善微阵列技术的生物信息学。这一设施将使研究人员和他们的学生能够一次可视化数千个基因的基因表达模式，并对加州大学洛杉矶分校的细胞和分子生物学研究产生重大影响。

An integrated microarraying facility will be initiated in the Department of Molecular and Medical Pharmacology (DMMP) in the Center for Health Sciences (CHS) at UCLA. The facility will consist of a DNA processing robot, a microarrayer, a scanner, a DNA/clone resource, and a computational facility. The microarray facility has been designed to provide the highest practicable throughput of this powerful technology.The research will cover the whole range of modern biology including studies of retroviruses, differentiation of neural stem cells and other cells, the cellular response to metals, synaptic transmission, neural growth factors, nitrous oxide physiology, immune system differentiation, neural aspects of behavior and glucocorticoid signaling. An important part is to improve the bioinformatics of microarray technologies using the data provided by the facility.This facility will provide researchers and their students the ability to visualize gene expression patterns for thousands of genes at once and have a major impact on research in cell and molecular biology at UCLA.