Acquisition of a Nanoparticle Analysis Ensemble
Acquisition of a Nanoparticle Analysis Ensemble
批准号:
0079612
负责人:
Theodore Randolph
金额:
$19.25万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2000
资助国家:
美国
项目状态:
已结题
起止时间:
2000-09-01 至 2002-08-31
中文摘要
CTS-0079612西奥多·W·兰道夫彩色核磁共振大学:收购纳米颗粒分析系统摘要这笔赠款支持购买一组仪器,这些仪器提供各种类型的微粒和纳米颗粒的分析和表征能力。一种名为Quantachrome Autosorb 1-C的仪器是一种多功能仪器,用于通过气体吸附/解吸方法确定表面积和孔径分布以及表面位置属性。第二种是ZetaPlus,可以测量胶体尺寸到30微米直径的颗粒上的Zeta电位。该设备具有相分析光散射选项,可提高电泳迁移率测量的灵敏度。第三项收购是Aerosizer DSP干粉粒度分析仪,它结合了激光光学技术对颗粒进行超音速气体夹带,可以测量0.2至700微米的颗粒尺寸分布。乐团中的最后一件是TSI杰玛方法尺寸分析器。该装置产生悬浮颗粒的气溶胶,干燥液滴,然后测量剩余颗粒在电场中的迁移率。这里的尺寸测量下限相当于一个相对分子质量为6000的蛋白质分子。纳米技术有望在许多实用领域取得进展。使用这些仪器对纳米颗粒进行表征的研究人员正在探索在高温合成新陶瓷材料、基因治疗、受控药物输送、粉末中蛋白质稳定、纳米颗粒材料的生产和治疗以及生物技术方面的应用。这些高灵敏度测量仪器的使用提高了其观测的准确性和精确度,并增强了其结果的重要性。
英文摘要
CTS-0079612Theodore W. RandolphUniversity of ColoradoMRI: Acquisition of a Nanoparticle Analysis EnsembleAbstractThis grant supports the purchase of a group of instruments that provide the capability of analysis and characterization of various types of microparticles and nanoparticles. One instrument , a Quantachrome Autosorb 1-C, is a multipurpose device for determining surface areas and pore-size distributions as well as surface-site properties by gas adsorption/desorption methods. A second, a ZetaPlus, can measure zeta potential on particles from colloidal size up to 30-microns diameter. This device has a phase-analysis light-scattering option that increases the sensitivity of electrophoretic mobility measurements. A third acquisition is an Aerosizer DSP dry powder size analyzer, with supersonic gas entrainment of particles combined with laser optics, which can measure particle-size distributions from 0.2 to 700 microns. The last item in the ensemble is a TSI GEMMA-method size analyzer. This device creates an aerosol of suspended particles, dries the droplets, and then measures mobility of the remaining particles in an electric field. The lower limit on size measurement here corresponds to a protein molecule with molecular weight of 6000.Nanotechnology promises advances in many practical fields. The researchers using these instruments for characterization of nanoparticles are exploring applications in high-temperature synthesis of new ceramic materials, gene therapy, controlled drug delivery, protein stabilization in powders, production and treatment of nanoparticulate materials, and biotechnology. The availability of these highly sensitive measurement instruments increases the accuracy and precision of their observations and enhances the significance of their results.
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会议论文
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依托单位:
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海外基金