A Core Equipment Facility for Cellular and Molecular Neuroscience

该奖项为购买设备提供支持，这些设备将用于建立用于细胞和分子生物学研究的多用户综合核心设备设施。设备包括离心机、显微注射装置、分光光度计和倒置显微镜。 该设施将由两个部门的教师共享：新成立的细胞生物学和神经科学系以及现有的化学和生物化学系。所有这些研究者的一个共同焦点是阐明神经发育和/或神经再生的细胞和分子机制。所有人现在都位于相邻的实验室，鉴于他们的研究方法重叠，将能够共享通过该奖项支持的设备。请批的主要装备中，有些将替换使用近25年、年久失修的现有装备，另一些将提供新的或扩大的能力。所有主要用户都是NSF赞助的IGERT博士培训计划的成员。该计划旨在培养研究生从多个层面，从分子到系统水平，使用来自细胞和分子生物学，结构生物学，计算生物学和系统神经科学的各种方法来处理生物学问题。 因此，IGERT受训人员将从获得课程工作和论文研究中使用的设备中受益匪浅。 该设备也将提供给一些本科生谁承担独立的研究项目，作为他们的教育的一部分使用。

This award provides support for purchase of equipment to be used to establish a multi-user, integrated core equipment facility for cellular and molecular biological research. The equipment includes centrifuges, a microinjection apparatus, a spectrophotomer and an inverted microscope. The facility will be shared by faculty in two departments: a newly formed Department of Cell Biology and Neuroscience and an existing Department of Chemistry and Biochemistry. A shared focus of all these investigators is the elucidation of the cellular and molecular mechanisms underlying neural development and/or nerve regeneration. All are now physically located in adjacent labs, and given the overlap in their research methodologies, will be able to share the equipment supported through this award.. Some of the major equipment items requested would replace existing items that are close to 25 years old and in serious disrepair, while others will provide new or expanded capabilities. All major users are members of the NSF sponsored IGERT doctoral training program at the University. This program in Complex Biological Systems is designed to train graduate students to approach biological problems from a multitude of levels, from the molecular to the systems level, using a variety of approaches drawn from cellular and molecular biology, structural biology, computational biology and systems neuroscience. Thus the IGERT trainees will benefit considerably from access to the equipment which will be used in both course work and in thesis research. The equipment will also be available for use by a number of undergraduate students who undertake independent research projects as part of their education.