Methods for Analyzing Lethal Gases of Endophytes

蒙大拿州立大学植物科学系的Gary a . Strobel教授将在这项由有机和大分子化学计划支持的探索性研究（SGER）小额资助中，捕获、分离和表征由白Muscodor alba产生的挥发性物质，白Muscodor alba是一种从霍诺都兰雨林中分离出来的新真菌属和物种。已经证明，白孢杆菌产生的至少一种气体化合物对其植物宿主茎组织中存在的几乎所有其他内生真菌和细菌都是致命的。将对具有抗菌活性的挥发性成分进行分离和鉴定。在有机和大分子化学项目的支持下，蒙大拿州立大学植物科学系的Gary a. Strobel教授将分离并鉴定一种新的真菌M. alba产生的挥发性有机化合物。这种气体物质的混合物已被证明对一系列其他真菌和细菌是致命的。生物活性产物的分离可能导致鉴定具有潜在药物应用的化合物，包括抗菌剂。

In this Small Grant for Exploratory Research (SGER) supported by the Organic and Macromolecular Chemistry Program, Professor Gary A. Strobel of the Department of Plant Sciences at Montana State University, will trap, isolate and characterize the volatile substances produced by Muscodor alba, a new fungal genus and species isolated from the Honoduran rainforest. It has been demonstrated that at least one of the gaseous compounds produced by M. alba is lethal to virtually all other endophytic fungi and bacteria that are present in the stem tissues of its plant host. The separation and identification of the volatile components possessing antimicrobial activity will be pursued.With the support of the Organic and Macromolecular Chemistry Program, Professor Gary A. Strobel, of the Department of Plant Sciencs at Montana State University, will isolate and identify volatile organic compounds produced by a new fungal species, M. alba. This mixture of gaseous substances has been shown to be lethal to a range of other fungi and bacteria. Isolation of the bioactive product(s) may result in the identification of compounds with potential pharmaceutical applications, including antimicrobial agents.