MRI: Acquisition of a CCD Single Crystal X-ray Diffraction System for a Partnership of Maine Institutions

在主要研究仪器(MRI)计划的支持下，科尔比学院化学系将获得一台带有CCD探测器的X射线衍射仪，用于小分子衍射仪。缅因州的五所教育机构将使用这种设备：科尔比学院、贝茨学院、鲍登学院、南缅因州大学和缅因州大学。X射线-ccd衍射仪将加强多个领域的研究，包括1)铜-芳烃化学的研究；2)选定天然产物的新合成方法；3)具有特殊结构的多环笼状化合物的合成；4)金属酶和金属酶模拟物的结构-功能关系；以及5)C-2对称稀土催化剂体系的生产及其在构建手性分子中的应用。X射线衍射仪可以精确和精确地测量分子的全部三维结构，包括键的距离和角度，并提供关于分子相对于邻近分子的空间排列的准确信息。这些研究将对许多领域产生影响，包括有机和天然产品合成以及生物、有机金属和无机化学材料领域。该文书将在所有参与机构的研究工作中发挥重要的辅助作用，这些机构从学士学位到授予博士学位的学校都有。此外，衍射系统将用于高级化学课程学生的正规教育，利用衍射仪的异地运行能力。

With support from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at Colby College will acquire a X-ray diffractometer with CCD detector for small molecule diffractometry. This equipment will be used by five educational institutions in Maine: Colby College, Bates College, Bowdoin College, the University of Southern Maine and the University of Maine. The X-ray CCD diffractometer will enhance research in a number of areas including 1) studies of copper-arene chemistry; 2) development of new synthetic methods of selected natural products; 3) synthesis of polycyclic cage compounds with unusual architecture; 4) structure-function relationships in metalloenzymes and metalloenzymes mimics; and 5) production of C-2 symmetric lanthanocene catalyst systems and their utility in the construction of chiral molecules. The X-ray diffractometer allows accurate and precise measurements of the full three dimensional structure of a molecule, including bond distances and angles, and it provides accurate information about the spatial arrangement of the molecule relative to the neighboring molecules. These studies will have an impact in a number of areas, including organic and natural products synthesis plus biological, organometallic and materials areas of inorganic chemistry. The instrument will play a major supporting role in the research efforts of all of the participating institutions, which range from bachelor's level to Ph.D.-granting schools. In addition, the diffraction system will be used for the formal education of students in advanced chemistry courses utilizing the capability of the diffractometer to be run off site.