Upgrade of Departmental Multi-User NMR Instrumentation

凭借化学研究仪器和设施（CRIF）计划的这一奖项，加州大学伯克利分校化学系将升级两台400 MHz NMR光谱仪，配备新的控制台和可变温度功能。这些设备将使教师能够在以下领域进行研究：a）化学计量和催化有机金属反应的探索性和机理研究; B）通过化学选择性连接合成糖肽模拟物; c）磺胺和亚磺酰胺在不对称合成和平行合成中的应用; d）树枝状聚合物的制备、表征和使用; e）金属-超分子组装体的结构和动力学;和f）钴介导的合成。 核磁共振（NMR）光谱是化学家用来阐明分子结构的最有力的工具。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。 对于从事前沿研究的化学家来说，使用最先进的NMR光谱仪是必不可少的。这些NMR研究的结果将对包括催化和材料化学在内的许多领域产生影响。

With this award from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at the University of California in Berkeley will upgrade two 400 MHz NMR Spectrometers with new consoles and variable temperature capabilities. This equipment will enable faculty to carry out research in the following areas: a) exploratory and mechanistic studies of stoichiometric and catalytic organometallic reactions; b) synthesis of glycopeptide mimics by chemoselective ligation; c) applications of sulfonamides and sulfinamides to asymmetric synthesis and parallel synthesis; d) preparation, characterization and use of dendrimers; e) structure and dynamics of metallo-supramolecular assemblies; and f) cobalt-mediated syntheses. Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in a number of areas including catalysis and materials chemistry.