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Purchase of an Nuclear Magnetic Resonance Spectrometer

Purchase of an Nuclear Magnetic Resonance Spectrometer
购买核磁共振波谱仪
批准号:
0131138
负责人:
Robert Scott
金额:
$16.65万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2002
资助国家:
美国
项目状态:
已结题
起止时间:
2002-02-01 至 2005-01-31

项目摘要

项目成果

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中文摘要
翻译
有了化学研究仪器和设施(CRIF)计划的这一奖项,格鲁吉亚大学化学系将获得一台300 MHz NMR光谱仪。该设备将使研究人员能够进行以下研究:a)用小分子和光探测细胞功能(Dore); B)评估阴离子受体的结合亲和力和选择性;新有机材料的表征;卟啉树枝状聚合物的结构弛豫研究(约翰逊); c)生物活性天然产物的全合成(Majetich); d)酶反应机理和动力学(菲利普斯); e)合成和结构有机金属化学(罗宾逊);和f)烷烃活化和无金属超分子催化。 核磁共振(NMR)光谱是化学家用来阐明分子结构的最有力的工具。它用于识别未知物质,表征分子内原子的特定排列,并研究溶液中分子之间相互作用的动力学。 对于从事前沿研究的化学家来说,使用最先进的NMR光谱仪是必不可少的。这些核磁共振研究的结果将在许多领域产生影响,包括生物化学和新催化剂和新材料的开发。
英文摘要
With this award from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at the University of Georgia will acquire a 300 MHz NMR Spectrometer. This equipment will enable researchers to carry out studies on a) probing cellular function with small molecules and light (Dore); b) assessment of binding affinity and selectivity of anion receptors; characterization of new organic materials; structure-relaxivity studies of porphyrin dendrimers (Johnson); c) total synthesis of biologically active natural products (Majetich); d) enzyme reaction mechanisms and kinetics (Phillips); e) synthesis and structural organometallic chemistry (Robinson); and f) alkane activation and metal-free supramolecular catalysis. Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in a number of areas including biochemistry and the development of new catalysts and novel materials.
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