Purchase of a High Field Nuclear Magnetic Resonance Spectrometer

学术研究基础设施项目的这一奖项将帮助耶鲁大学化学系获得一台750 MHz核磁共振光谱仪，该光谱仪将用于研究。将支持的研究活动包括：耶鲁核心研究(I)高极化样品的核磁共振，多氢化物和催化剂(II)磁场诱导有序介质中结构的测定(III)RNA和蛋白质-RNA络合物结构的核磁共振研究(IV)RNA和核糖核蛋白结构的核磁共振测定(V)生物膜中苯二酮取向的核磁共振研究(VI)外部用户(学术界和工业界)对无定形氧化铝和介孔分子筛研究的比较(I)用750 MHz光谱仪进行生物体系的固体核磁共振研究(Ii)DNA和蛋白质的核磁共振研究(Iii)低维导体中的探测结构(Iv)酸和碱催化剂的研究(V)分子间相干转移(Vi)沸石中过渡金属络合物的亲核取代机理(Vii)薄膜材料的高场光泵核磁共振核磁共振波谱是化学家用来解释分子结构的最有力的工具。它被用来识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱是必不可少的。这些核磁共振研究的结果在聚合物和催化等领域以及生物学中都是有用的。

This award from the Academic Research Infrastructure Program will help the Department of Chemistry at Yale University acquire a 750 MHz NMR Spectrometer which will be used in research. The research activity to be supported includes: Yale Core Research (i) NMR in Highly Polarized Samples, Polyhydrides and Catalysts (ii) Structure Determination in Media with Magnetic Field Induced Order (iii) NMR Studies of the Structured of RNA and Protein-RNA Complexes (iv) Determination of the Structures of RNA's and Ribonucleoproteins by NMR (v) NMR Studies of Quinone Orientation in Biological Membranes (vi) A Comparison of Amorphous Alumina and Mesoporous Molecular Sieves Research by Outside Users (Academic and Industrial) (i) Solids NMR Studies of Biological Systems Using a 750 MHz Spectrometer (ii) NMR Studies of DNA and Proteins (iii) Probing Structure in Low-Dimensional Conductors (iv) The Study of Acid and Basic Catalysts (v) Intermolecular Coherence Transfer (vi) Nucleophilic Substitution Mechanisms of Transition Metal Complexes in Zeolites (vii) High Field Optically Pumped NMR of Thin Film Materials Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research. The results from these NMR studies are useful in the areas such as polymers and catalysis, and in biology.