Porphyrins, Carbaporphyrins and Related Conjugated Macrocycles

本研究的重点是开发具有融合芘环的卟啉的制备方法，并测试使用芘作为连接融合卟啉环的平台的潜力。在平行研究中，将研究碳卟啉的合成、表征和化学性质。其他大环体系，包括tropiporphyrin，将采用“3+1”方法合成，“4+1”方法将用于制备扩展卟啉的碳-类似物。本科生将参与研究的所有阶段。有机和大分子化学项目通过更新本科院校研究（RUI）奖，支持伊利诺伊州立大学化学系Timothy D. Lash博士的研究工作。拉什博士将专注于卟啉类发色团和相关二聚体或低聚体系统的制备。卟啉是一类色彩鲜艳的杂环化合物，在自然界中具有多种功能，其类似物的合成为制备具有潜在有趣性质的化合物开辟了新的途径。这项工作将在本科生和硕士研究生的合作下进行。

The focus of this research is to develop methodology for the preparation of porphyrins with fused pyrene rings and to test the potential for using pyrene as a platform for connecting fused porphyrin rings. In parallel studies, the synthesis, characterization and chemistry of carbaporphyrins will be investigated. Other macrocyclic systems, including tropiporphyrin, will be synthesized using "3+1" methodology and "4+1" methodology will be used to prepare carba-analogues of expanded porphyrins. Undergraduate students will be involved at all stages of the research.With this renewal Research in Undergraduate Institutions (RUI) award, the Organic and Macromolecular Chemistry Program is supporting the research efforts of Dr. Timothy D. Lash of the Department of Chemistry at Illinois State University. Dr. Lash will focus his work on the preparation of porphyrin-like chromophores and related dimeric or oligomeric systems. Porphyrins are a class of brightly colored heterocycles that serve a variety of functions in nature and the synthesis of analogues opens new avenues for the preparation of compounds with potentially interesting properties. The work will be carried out with the collaboration of undergraduate and masters level graduate students.