SBIR Phase I: Urea Sensing Biocatalytic Polymers

该小型企业创新研究（SBIR）第一期项目建议使用酶聚氨酯聚合物开发尿素传感器。该产品的概念是廉价的，非常容易使用，不需要额外的分析设备或电力。其配方中使用的酶的严格特异性将为传感器提供检测尿素的高精度，并应限制假阳性和阴性信号。表面和溶液的取样仅需一个简单的步骤，从而限制了用户出错的可能性。最后，几分钟量级的快速响应时间将与传感器的目标应用很好地对应。该项目的商业应用将在与食品服务业和卫生保健机构有关的监管测试领域。由于洗手间的不当清洁做法可能导致细菌污染，因此在医院浴室设施中使用尿素检测传感器可能有助于降低患者感染率。

This Small Business Innovation Research (SBIR)Phase Iproject proposes to develop a urea sensor using enzyme polyurethane polymers. The product concept is inexpensive, very easy to use and requires no additional analytical equipment or electricity. The strict specificity of the enzymes used in its formulation will provide the sensor with high precision in detecting urea and should limit false positive and negative signals. Sampling of surfaces and solutions will require only 1 simple step, limiting the potential for user error. Finally, rapid response times, on the order of a few minutes, will correspond well with the target applications of the sensor. The commercial applications of this project will be in the area of regulatory testing linked to the food service industry and health care establishments. Because improper cleaning practices of restrooms can lead to bacterial contamination, the use of urea-detecting sensors in hospital bathroom facilities may aid in reducing patient infection rates.