SBIR Phase I: Enhanced Spectral Interferometry for Biological Imaging

0214911KaneThis小企业创新研究第一阶段项目建议开发一种用于生物和生物医学应用的增强型光谱干涉测量方法。这种方法将提供快速、高分辨率的光学成像，并且可以容易地与光纤耦合，用于使用内窥镜、导管和类似装置的体内应用。第一阶段项目将演示增强光谱干涉测量在生物组织横截面成像中的实用性。第二阶段计划将发展一套高速光纤成像光谱干涉仪，其商业应用领域为生物医学仪器及设备。该技术将应用于各种生物医学研究和临床需求，包括监测组织对药物或辐射暴露的反应，检测癌组织和癌前组织，以及静脉和动脉结构和眼部病变的成像。

0214911KaneThis Small Business Innovation Research Phase I Project proposes to develop an enhanced spectral interferometry method for biological and biomedical applications. This method will provide rapid, high resolution optical imaging and can be easily coupled with fiber optics for in-vivo applications using endoscopes, catheters and similar devices. The Phase I Project will demontrate the utility of enhance spectral interferometry for cross-sectional imaging in biological tissues. In the follow on Phase II Project, a fiberoptic imaging spectral interferometer capable of high speed will be developed.The commercial applications of this project are in the area of biomedical devices and instrumentation. This technology will be applied to a variety of biomedical research and clinical needs including monitoring of tissue response to drugs or radiation exposure, detection of cancerous and pre-cancerous tissues, and the imaging of venous and arterial structures and ocular pathologies.