RUI: Supramolecular Utility of a Versatile New Electron Acceptor

在化学系有机动力学计划的支持下，芒特霍利奥克学院的达伦·汉密尔顿教授将继续一项专门围绕滑石三亚胺的合成和物理化学建立的研究计划，这是PI实验室开发的一种新的电子受体，并于2001年首次发表。根据观察，这些新的三酰亚胺在结构和功能上可能与苯、萘和茂的二亚胺一起分类，因此计划了一个重要的研究计划。这些结构受到了极大的关注，主要是因为它们具有很强的接受电子的性质。它们在超分子化学众多研究领域的发展中发挥了关键作用，涉及到拓扑和分子尺度机械、电子材料、氧化还原活性生物辅助因子的模拟、DNA插入器和传感器等领域。提出的研究计划的总体目标是通过展示通往核心的可行途径，并表征其衍生物和可能产生的分子组装的紧急性质，将新的三亚胺构建块全面引入这一多样化的领域。基于三亚胺平台的研究项目将为本科生提供刺激和多样化的实验室体验，涉及合成、光谱和材料表征。这项工作将让参与者有一个重要的机会了解当代不断扩大的研究探索领域，并将有助于促进曼荷莲学院化学的强大准备传统。有机化学和高分子化学项目支持曼荷莲学院的达伦·汉密尔顿教授，他计划在本科学院广泛影响研究型学术的两个关键要素。首先，通过包含既演示重要概念又为更大的研究项目提供有用材料的模块，来活跃所有学生所做的实验序列。第二，尝试在大学生涯早期发现并鼓励那些以前没有考虑过参与研究的可能性的学生，或者一直不愿向前迈进的学生。利用这种接触机制，女本科生将被鼓励考虑她们参与研究项目的问题，通过参加暑期项目，或通过监督独立学习。截至十年前，美国每四名女性化学家中就有一人毕业于芒特霍利奥克学院，该学院仍然是女性博士化学家最多产的来源之一。

With the support of the Organic Dynamics Program in the Chemistry Division, Professors Darren Hamilton at Mount Holyoke College will continue a research program that is built exclusively around the synthetic and physical chemistry of mellitic triimides, a new class of electron acceptors developed in the PI's laboratory and published for the first time in 2001. A significant program of study is planned based the observation that these new triimides may be classed, structurally and functionally, with the diimides of benzene, naphthalene, and perylene. These structures have received a great deal of attention, principally due to their strongly electron accepting nature. They have played key roles in the development of numerous areas of investigation in supramolecular chemistry, involving areas such as topology and molecular scale machinery, electronic materials, mimics of redox active biological co-factors, DNA intercolators, and sensors. The overarching aim of the program of study proposed is to fully introduce the new triimide building block to this diverse arena by demonstrating viable access to the core, and characterizing emergent properties in its derivatives and the molecular assemblies that may result. Research projects based on the triimide platform will provide stimulating and varied laboratory experiences for undergraduates that will involve synthesis, spectroscopy, and materials characterization. The work will give participants an important glimpse of an expanding contemporary area of research inquiry, and will contribute to the strong tradition of preparation that characterizes chemistry at Mount Holyoke College..The Organic and Macromolecular Chemistry Program supports Professor Darren Hamilton at Mount Holyoke College who plans to broadly impact two key elements of research-based scholarship in an undergraduate college. First, to enliven the experimental sequence taken by all students by including modules that both demonstrate important concepts and provide materials of use to the larger research program. Second, to attempt to identify and encourage students early in their college careers who have not previously considered the possibility of involvement in research, or who have been reluctant to step forward. Using this mechanism of exposure, female undergraduates will be encouraged to consider the question of their involvement with a research program, through participation in a summer program, or through supervised independent study. As of a decade ago, one in four women chemists in the US graduated from Mount Holyoke College, and the college remains one of the most productive sources of women PhD chemists.