MRI: Acquisition of a CCD X-ray Diffractometer

在重大研究仪器（MRI）计划的支持下，贝勒大学化学和生物化学系将获得一台带有CCD探测器的X射线衍射仪。这一设备将加强若干领域的研究，包括：a）新的有机金属物质的合成和特性，特别是可连接在一起形成树枝状聚合物、聚合物和其他超分子物质的阴离子化合物; B）过渡金属的“半夹心”单碳交酯络合物的化学研究; c）设计用于癌症化疗的新的血管靶向剂;和d）开发用于感测含水基质中的离子污染物的化学改性电极阵列。X射线衍射仪可以精确测量分子的完整三维结构，包括键距和角度，并提供有关分子相对于相邻分子的空间排列的准确信息。这些研究将在许多领域产生影响，特别是药物化学和材料化学。

With support from the Major Research Instrumentation (MRI) Program, the Department of Chemistry and Biochemistry at Baylor University will acquire a X-ray diffractometer with CCD detector. This equipment will enhance research in a number of areas including the following: a) the synthesis and characterization of new organometallic species, especially anionic compounds that may be linked together for the formation of dendrimers, polymers and other supramolecular species; b) the study of the chemistry of 'half sandwich' monocarbollide complexes of transition metals; c) the design of new vascular targeting agents for cancer chemotherapy; and d) the development of chemically modified electrode arrays for sensing ionic contaminants in aqueous matrices. The X-ray diffractometer allows accurate and precise measurements of the full three dimensional structure of a molecule, including bond distances and angles, and it provides accurate information about the spatial arrangement of the molecule relative to the neighboring molecules. These studies will have an impact in a number of areas, especially medicinal chemistry and materials chemistry.