Collaborative Research: Relationship Among Demographic, Social and Genetic Structure

苏珊·C·阿尔贝茨和珍妮·阿尔特曼：提案编号0322781(阿尔特曼)/0322613(阿尔伯茨)，合作研究：人口、社会和遗传结构之间的关系。行为在人类的生存和繁殖中起着举足轻重的作用。它的直接、短期影响是维持动态平衡和有机体的完整性，因为行为为个体提供了一种对其内部和外部环境变化做出快速和灵活反应的机制。更深刻的是，行为对个人生活和人口进化轨迹的长期影响。研究人员的主要长期目标是全面了解行为如何影响一种野生哺乳动物的健康结果和种群过程东非安博塞利盆地的稀树大草原狒狒。这项拟议的工作不仅将实现重要的短期目标，而且还将公开地向长期目标延伸。总体概念框架是一个综合的社会生态，对行为、生理、遗传结构和人口统计学之间的内在相互依赖关系非常敏感。在接下来的三年里，这项研究将(1)通过父系和母系更深入地探讨人际关系的功能和终身发展，(2)继续勾勒出两性终身健康差异的根源。这将通过测试从三个假设中得出的八个明确预测来实现。对于女性来说，这与社会地位以及父母和母亲亲属对健康的影响有关。对于男性，他们解决了交配成功和亲子关系成功之间的关系，男性配偶选择在父子关系成功中的作用，以及男性对其后代存活的直接行为贡献。遗传和生理分析基于非侵入性生物采样以及相关的分析和基因分型技术，这些技术的发展和完善一直是这些研究小组的基石。

Susan C. Alberts and Jeanne Altmann: Proposal number 0322781(Altmann)/0322613(Alberts), Collaborative Research: Relationship among demographic, social and genetic structure. Behavior plays a pivotal role in survival and reproduction. Its immediate, short-term impact is in maintaining homeostasis and organismal integrity as behavior provides the individual with a mechanism of rapid and flexible response to changes in its internal and external environments. Even more profound is behavior's long-term impact on the lives of individuals and on the evolutionary trajectories of populations. The main long-term objective of the investigators is to develop a comprehensive picture of how behavior shapes fitness outcomes and population processes in one population of wild mammals - the savanna baboons of the Amboseli basin in east Africa. The proposed work not only will accomplish important short-term goals but will reach overtly toward the long-term ones as well.The overall conceptual framework is an integrative socioecology that is sensitive to the intrinsic interdependencies among behavior, physiology, genetic structure, and demography. During the next three years, the research will (1) probe more deeply into the function and lifetime development of relationships through individuals' paternal as well as maternal lineage and (2) continue to delineate sources of lifetime fitness differences for both sexes. This will be accomplished by testing eight explicit predictions derived from three hypotheses. For females, these relate to the impact of social status and of paternal and maternal relatives on fitness. For males they address the relationship between mating success and paternity success, the role of male mate choice in paternity success, and the direct behavioral contributions that males make to the survival of their offspring. Genetic and physiological analyses are based on non-invasive biological sampling and associated assay and genotyping techniques, the development and refinement of which have been a cornerstone of these research groups.