CAREER: Vibrational Couplings and Conformational Dynamics of Solvated Systems

Martin Zanni教授将在威斯康星大学麦迪逊分校进行研究，研究使用飞秒激光的二维非线性红外光谱技术的发展。该奖项由化学学部实验物理化学项目支持。所开发的方法将用于研究溶液中DNA和RNA低聚物的振动动力学、偶联和折叠。此外，他还将对本科生、研究生和博士后进行研究培训，并与芝加哥一所市中心高中开展积极的外展合作。Zanni教授开发的方法对于研究复杂生物分子的动力学可能是非常普遍的。除了开发这些新的实验工具，Zanni教授还将在他的实验室指导高中和本科生的研究人员。他还将与芝加哥市中心的一所高中——贵族街特许学校（Noble Street Charter school）开展一项拓展计划。这所学校95%的学生都是少数族裔。Zanni教授将与学校的老师一起制定课程开发计划，将威斯康星大学纳米结构材料和界面材料研究科学与教育中心开发的教学材料纳入其中。

In this CAREER award, supported by the Experimental Physical Chemistry Program of the Chemistry Division, Prof. Martin Zanni will conduct research, at the University of Wisconsin, Madison, on the development of the technique of two-dimensional non-linear infrared spectroscopy using femtosecond lasers. The methods developed will be used to study the vibrational dynamics, couplings and folding of DNA and RNA oligomers in solution. In addition, he will train undergraduate, graduate and post-doctoral students in research and develop an active outreach collaboration with an inner-city high school in Chicago. The methods developed by Prof. Zanni may prove to be quite general for studying the dynamics of complex biological molecules. Besides developing these new experimental tools, Prof. Zanni will mentor high-school and undergraduate researchers in his laboratory. He also will begin an outreach program with an inner-city Chicago high school, the Noble Street Charter School. This school has a student body that is 95% underreprensented minority. Prof. Zanni will work with the teachers at the school on a curriculum development plan, incorporating the instructional materials developed by the Material Research Science and Education Center on Nanostructured Materials and Interfaces at the University of Wisconsin.